TFA-Mediated Tandem Friedel-Crafts Alkylation/Cyclization/Hydrogen Transfer Process for the Synthesis of Flavylium Compounds.

TFA-Mediated Tandem Friedel-Crafts Alkylation/Cyclization/Hydrogen Transfer Process for the Synthesis of Flavylium Compounds. Research Abstract Details 

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TFA-Mediated Tandem Friedel-Crafts Alkylation/Cyclization/Hydrogen Transfer Process for the Synthesis of Flavylium Compounds. Abstract Text:

Yan-Chao Wu,Li Liu,Yu-Liang Liu,Dong Wang,Yong-Jun Chen,Yan-Chao Wu,Li Liu,Yu-Liang Liu,Dong Wang,Yong-Jun Chen,

The tandem reaction of phenols and chalcones in refluxing TFA gave the flavylium species of 2-hydroxy-2-phenyl-2H-chromenes in moderate to good isolated yields. The reaction was proposed to involve a tandem transformation of Friedel-Crafts alkylation, dehydrative cyclization, intermolecular hydrogen transfer, and hydration. As a multifunctional catalyst, TFA mediated the processes efficiently and cleanly.

TFA-Mediated Tandem Friedel-Crafts Alkylation/Cyclization/Hydrogen Transfer Process for the Synthesis of Flavylium Compounds. Publishing Authors By Initials

YC Wu,L Liu,YL Liu,D Wang,YJ Chen,YC Wu,L Liu,YL Liu,D Wang,YJ Chen,

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TFA-Mediated Tandem Friedel-Crafts Alkylation/Cyclization/Hydrogen Transfer Process for the Synthesis of Flavylium Compounds. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: The Journal of organic chemistry

VOLUME: 72

Page Numbers: 9383-6

Journal Abbreviation: J. Org. Chem.

ISSN: 0022-3263

DAY: 1

MONTH: 11

YEAR: 2007

TFA-Mediated Tandem Friedel-Crafts Alkylation/Cyclization/Hydrogen Transfer Process for the Synthesis of Flavylium Compounds. Information

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LANGUAGE: eng

NlmUniqueID: 2985193

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AFFILIATION: Beijing National Laboratory for Molecular Science (BNLMS), Center for Chemical Biology, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100080, People's Republic of China lliu@iccas.ac.cn; yjchen@iccas.ac.cn.

Country: United States

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MEDLINETA: J Org Chem

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