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Tetrahymena calcium-binding protein is indeed a calmodulin.

Tetrahymena calcium-binding protein is indeed a calmodulin. Research Abstract Details 

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  • Tetrahymena calcium-binding protein is indeed a calmodulin. Abstract Text:

    y suzukiY Suzuki,s nagaoS Nagao,k abeK Abe,t hirabayashiT Hirabayashi,y watanabeY Watanabe,

    We previously isolated a Ca2+-binding protein from a ciliate, Tetrahymena, and designated it as TCBP (Tetrahymena Ca2+-binding protein). The present paper reports that TCBP, which has two high affinity Ca2+-binding sites (Kd=4.6 X 10(-6) M), could activate porcine brain cyclic nucleotide phosphodiesterase at a concentration of over 10(-6) M free Ca2+, with the same mode of activation as that of authentic (porcine brain) calmodulin. In addition, the amino acid composition of TCBP was essentially the same as that of brain calmodulin. Therefore, we conclude that TCBP as an activator of Tetrahymena guanylate cyclase is indeed a calmodulin.

    Tetrahymena calcium-binding protein is indeed a calmodulin. Publishing Authors By Initials

    y suzukiY Suzuki,s nagaoS Nagao,k abeK Abe,t hirabayashiT Hirabayashi,y watanabeY Watanabe,

    For similar animals: invertebrates: protozoa: ciliophora: oligohymenophorea: hymenostomatida: tetrahymenina: tetrahymena: tetrahymena pyriformis research abstracts see: animals: invertebrates: protozoa: ciliophora: oligohymenophorea: hymenostomatida: tetrahymenina: tetrahymena: tetrahymena pyriformis research

    PUBMED ID PMID:

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    Tetrahymena calcium-binding protein is indeed a calmodulin. Journal Published:

    PUBLICATION TYPE: Journal Article

    Journal: Journal of biochemistry

    VOLUME: 89

    Page Numbers: 333-6

    Journal Abbreviation: J. Biochem.

    ISSN: 0021-924X

    DAY: 19

    MONTH: Jan

    YEAR: 1981

    Tetrahymena calcium-binding protein is indeed a calmodulin. Information

    Number of References:

    LANGUAGE: eng

    NlmUniqueID: 376600

    Tetrahymena calcium-binding protein is indeed a calmodulin. Keywords Mesh Terms:

    KEYWORDS: Tetrahymena pyriformis

    MESH TERMS: metabolism

    Chemical & Substance for Abstract: Tetrahymena calcium-binding protein is indeed a calmodulin. Information

    Substance Name: Guanylate Cyclase

    Registry Number: EC 4.6.1.2

    Grant and Affiliation Information for Tetrahymena calcium-binding protein is indeed a calmodulin.

    AFFILIATION:

    Country: JAPAN

    JAPAN Research PublicationJAPAN Research Publication

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    MEDLINETA: J Biochem

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