Test-retest reliability of the prolactin and cortisol responses to D,L-fenfluramine challenge in disruptive behavior disorders.

Test-retest reliability of the prolactin and cortisol responses to D,L-fenfluramine challenge in disruptive behavior disorders. Research Abstract Details 

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Test-retest reliability of the prolactin and cortisol responses to D,L-fenfluramine challenge in disruptive behavior disorders. Abstract Text:

We examined the intraindividual stability of plasma prolactin (PRL) and cortisol responses to D,L-fenfluramine challenges (1.0 mg/kg, p.o.), at a 1-week interval, in boys with disruptive behavior disorders. Two acute administrations of fenfluramine produced consistent and predictable effects on net prolactin responses (peak delta PRL, area under the curve delta PRL), but variable and unpredictable effects on net cortisol responses. The time course and magnitude of fenfluramine blood levels, not nor-fenfluramine, paralleled net PRL responses to fenfluramine. These data indicate that the PRL response to fenfluramine shows continuity within individuals over the course of 1 week, providing a reliable index to reflect the overall function of the serotonin system in the limbic-hypothalamus.

Test-retest reliability of the prolactin and cortisol responses to D,L-fenfluramine challenge in disruptive behavior disorders. Publishing Authors By Initials

For similar hormones, hormone substitutes, and hormone antagonists: hormones: peptide hormones: gonadotropins: gonadotropins, pituitary: prolactin research abstracts see: hormones, hormone substitutes, and hormone antagonists: hormones: peptide hormones: gonadotropins: gonadotropins, pituitary: prolactin research

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Test-retest reliability of the prolactin and cortisol responses to D,L-fenfluramine challenge in disruptive behavior disorders. Journal Published:

PUBLICATION TYPE: Research Support, U.S. Gov't,

Journal: Psychiatry research

VOLUME: 42

Page Numbers: 65-72

Journal Abbreviation: Psychiatry Res

ISSN: 0165-1781

DAY: 17

MONTH: Apr

YEAR: 1992

Test-retest reliability of the prolactin and cortisol responses to D,L-fenfluramine challenge in disruptive behavior disorders. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 7911385

Test-retest reliability of the prolactin and cortisol responses to D,L-fenfluramine challenge in disruptive behavior disorders. Keywords Mesh Terms:

KEYWORDS: Prolactin

MESH TERMS: blood

Chemical & Substance for Abstract: Test-retest reliability of the prolactin and cortisol responses to D,L-fenfluramine challenge in disruptive behavior disorders. Information

Substance Name: Prolactin

Registry Number: 9002-62-4

Grant and Affiliation Information for Test-retest reliability of the prolactin and cortisol responses to D,L-fenfluramine challenge in disruptive behavior disorders.

AFFILIATION: Medical College of Pennsylvania Eastern Pennsylvania Psychiatric Institute, Department of Psychiatry, Philadelphia.

Country: IRELAND

AGENCY: United States NIMH

GRANT: MH-00590

ACRONYM: MH

MEDLINETA: Psychiatry Res

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