Technique for measuring hippocampal T2 relaxation time.

Technique for measuring hippocampal T2 relaxation time. Research Abstract Details 

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Technique for measuring hippocampal T2 relaxation time. Abstract Text:

C R Jack,

PURPOSE: To implement and validate methods for producing calculated coronal T2 maps with complete coverage of the hippocampus and the rest of the brain. METHODS: T2 relaxation times were estimated on three occasions for 12 quality assessment test objects with the use of fast spin-echo (FSE) and conventional spin-echo (CSE) sequences. Hippocampal T2 relaxation times were measured in 15 healthy subjects with FSE and CSE sequences. Ten of these subjects were scanned twice with CSE imaging. Twenty-two patients with temporal lobe epilepsy, in whom hippocampal T2 relaxation times were previously estimated by means of a multiecho sequence, were studied with CSE. RESULTS: CSE data were more reliable than FSE data. Reliability of hippocampal T2 measures on repeated acquisitions was superior for the CSE sequence with echo time 30,120 than for the 30,80 sequence (test-retest reliability, 4.0%; interrater reliability, 4.6%). CSE images were suitable for qualitative reporting, so additional T2-weighted sequences were not required. There was good correlation between these hippocampal T2 data and values obtained on a previously validated multiecho technique, with reliable identification of hippocampal sclerosis. CONCLUSION: T2 mapping with CSE 30/120 sequences may be readily applied, produces reliable T2 values in contiguous 5-mm sections, and may be useful in the assessment of the hippocampus and other cerebral structures.

Technique for measuring hippocampal T2 relaxation time. Publishing Authors By Initials

CR Jack,

For similar pathological conditions, signs and symptoms: pathologic processes: sclerosis research abstracts see: pathological conditions, signs and symptoms: pathologic processes: sclerosis research

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Technique for measuring hippocampal T2 relaxation time. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: AJNR. American journal of neuroradiology

VOLUME: 17

Page Numbers: 1805-10

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ISSN: 0195-6108

DAY: 14

MONTH: 02

YEAR: 2008

Technique for measuring hippocampal T2 relaxation time. Information

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LANGUAGE: eng

NlmUniqueID: 8003708

Technique for measuring hippocampal T2 relaxation time. Keywords Mesh Terms:

KEYWORDS: Sclerosis

MESH TERMS: pathology

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Grant and Affiliation Information for Technique for measuring hippocampal T2 relaxation time.

AFFILIATION: MR Unit, National Society for Epilepsy, Institute of Neurology, Bucks, United Kingdom.

Country: UNITED STATES

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MEDLINETA: AJNR Am J Neuroradiol

REFSOURCE: AJNR Am J Neuroradiol. 1996 Nov-Dec;17(1

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