Taste receptors in the gastrointestinal tract. II. L-amino acid sensing by calcium-sensing receptors: implications for GI physiology.

Taste receptors in the gastrointestinal tract. II. L-amino acid sensing by calcium-sensing receptors: implications for GI physiology. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Taste receptors in the gastrointestinal tract. II. L-amino acid sensing by calcium-sensing receptors: implications for GI physiology. Abstract Text:

Arthur D Conigrave,Edward M Brown,

The extracellular calcium-sensing receptor (CaR) is a multimodal sensor for several key nutrients, notably Ca2+ ions and L-amino acids, and is expressed abundantly throughout the gastrointestinal tract. While its role as a Ca2+ ion sensor is well recognized, its physiological significance as an L-amino acid sensor and thus, in the gastrointestinal tract, as a sensor of protein ingestion is only now coming to light. This review focuses on the CaR's amino acid sensing properties at both the molecular and cellular levels and considers new and putative physiological roles for the CaR in the amino acid-dependent regulation of gut hormone secretion, epithelial transport, and satiety.

Taste receptors in the gastrointestinal tract. II. L-amino acid sensing by calcium-sensing receptors: implications for GI physiology. Publishing Authors By Initials

AD Conigrave,EM Brown,

For similar sensation: taste research abstracts see: sensation: taste research

PUBMED ID PMID:

MEDLINE DATE:

Taste receptors in the gastrointestinal tract. II. L-amino acid sensing by calcium-sensing receptors: implications for GI physiology. Journal Published:

PUBLICATION TYPE: Review

Journal: American journal of physiology. Gastrointestinal a

VOLUME: 291

Page Numbers: G753-61

Journal Abbreviation: Am. J. Physiol. Gastrointest.

ISSN: 0193-1857

DAY: 3

MONTH: Nov

YEAR: 2006

Taste receptors in the gastrointestinal tract. II. L-amino acid sensing by calcium-sensing receptors: implications for GI physiology. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 100901227

Taste receptors in the gastrointestinal tract. II. L-amino acid sensing by calcium-sensing receptors: implications for GI physiology. Keywords Mesh Terms:

KEYWORDS: Taste

MESH TERMS: physiology

Chemical & Substance for Abstract: Taste receptors in the gastrointestinal tract. II. L-amino acid sensing by calcium-sensing receptors: implications for GI physiology. Information

Substance Name: Receptors, G-Protein-Coupled

Registry Number: 0

Grant and Affiliation Information for Taste receptors in the gastrointestinal tract. II. L-amino acid sensing by calcium-sensing receptors: implications for GI physiology.

AFFILIATION: School of Molecular and Microbial Biosciences, University of Sydney, NSW 2006, Australia. a.conigrave@mmb.usyd.edu.au

Country: United States

AGENCY: United States NIDDK

GRANT: DK-67155

ACRONYM: DK

MEDLINETA: Am J Physiol Gastrointest Live

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Taste receptors in the gastrointestinal tract II L-amino acid sensing by calcium-sensing receptors: implications for GI physiology Related Publications

• A radioimmunoassay method for the determination of nedocromil sodium in plasma and urine.
• ABCB1 2677G>T/A genotype and paclitaxel pharmacogenetics in ovarian cancer.
• Age-related macular degeneration: self-management and reduction of depressive symptoms in a randomized, controlled study.
• Application of item response theory to quantify substance use disorder severity.
• Cell structure and mobilization of lipids and proteins from cotyledon under microgravity influence.
• Chemokine receptors : therapeutic potential in asthma.
• Circadian rhythms. Chronobiology--reducing time.
• Comparative gene expression by WC1+ gammadelta and CD4+ alphabeta T lymphocytes, which respond to Anaplasma marginale, demonstrates higher expression of chemokines and other myeloid cell-associated genes by WC1+ gammadelta T cells.
• Effect of gonadotrophin releasing hormone on conception rate in repeat-breeder dairy cows.
• Engineered iron oxide-adhesion mutants of the Escherichia coli phage lambda receptor.
• Epigenetic silencing of the tumor suppressor cystatin M occurs during breast cancer progression.
• From tip-of-the-tongue (TOT) data to theoretical implications in two steps: when more TOTs means better retrieval.
• Gravisensing: ionic responses, cytoskeleton and amyloplast behavior.
• Identifying housing that poisons: a critical step in eliminating childhood lead poisoning.
• Impaired trace and contextual fear conditioning in aged rats.
• In vivo metabolism of alpha-tocopherol in lipoproteins and liver: studies on rabbits in response to acute cholesterol loading.
• LIPID arrays: new tools in the understanding of membrane dynamics and lipid signaling.
• Loading and boundary condition influences in a poroelastic finite element model of cartilage stresses in a triaxial compression bioreactor.
• Meta-analysis of the effect of exercise interventions on fitness outcomes among adults with type 1 and type 2 diabetes.
• Prenatal diagnostic testing for infantile and late-infantile neuronal ceroid lipofusinoses (NCL) using allele specific primer extension (ASPE).
• Quantitative analysis reveals differential expression of mucin (MUC2) and intestinal trefoil factor mRNAs along the longitudinal axis of rat intestine.
• RHO SIGNALING in vascular diseases.
• Regio- and stereoselective glycosylation: synthesis of 5-haloimidazole alpha-ribonucleosides.
• Solid-state 2H NMR structure of retinal in metarhodopsin I.
• Spermagglutinins in serum and seminal fluid of bulls and their relationship to fertility classification.
• Stimulatory effect of genistein and apigenin on the growth of breast cancer cells correlates with their ability to activate ER alpha.
• Taste receptors in the gastrointestinal tract. II. L-amino acid sensing by calcium-sensing receptors: implications for GI physiology.
• Transforming growth factor beta receptor family ligands inhibit hepatocyte growth factor synthesis and secretion from astrocytoma cells.
• Treatment of the severe refractory irritable bowel patient.
• Working with a Head Start population with asthma: lessons learned.