Targeting the stromal fibroblasts: a novel approach to melanoma therapy.

Targeting the stromal fibroblasts: a novel approach to melanoma therapy. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Targeting the stromal fibroblasts: a novel approach to melanoma therapy. Abstract Text:

Keiran S M Smalley,Mercedes Lioni,Meenhard Herlyn,

Classically, cancer is thought of as a genetic disease, where the step-wise acquisition of mutations initiates and drives progression. More recent thinking posits that, although cancers are initiated through genetic mutation, progression is often the result of dynamic interactions between the tumor cells and their surrounding environment.

Targeting the stromal fibroblasts: a novel approach to melanoma therapy. Publishing Authors By Initials

KS Smalley,M Lioni,M Herlyn,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

Targeting the stromal fibroblasts: a novel approach to melanoma therapy. Journal Published:

PUBLICATION TYPE: Review

Journal: Expert review of anticancer therapy

VOLUME: 5

Page Numbers: 1069-78

Journal Abbreviation: Expert Rev Anticancer Ther

ISSN: 1744-8328

DAY: 5

MONTH: Dec

YEAR: 2005

Targeting the stromal fibroblasts: a novel approach to melanoma therapy. Information

Number of References: 82

LANGUAGE: eng

NlmUniqueID: 101123358

Targeting the stromal fibroblasts: a novel approach to melanoma therapy. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: Targeting the stromal fibroblasts: a novel approach to melanoma therapy. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Targeting the stromal fibroblasts: a novel approach to melanoma therapy.

AFFILIATION: The Wistar Institute, Philadelphia, PA 19104, USA. ksmalley@wistar.org

Country: England

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Expert Rev Anticancer Ther

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Targeting the stromal fibroblasts: a novel approach to melanoma therapy Related Publications

• Adenovirus infection enhances killing of melanoma cells by a mitotoxin.
• An organometallic protein kinase inhibitor pharmacologically activates p53 and induces apoptosis in human melanoma cells.
• CCN3 controls 3D spatial localization of melanocytes in the human skin through DDR1.
• Downregulation of CCN3 expression as a potential mechanism for melanoma progression.
• Dynamics of cell interactions and communications during melanoma development.
• Endothelial cells as targets for tumor therapy.
• Ki67 expression levels are a better marker of reduced melanoma growth following MEK inhibitor treatment than phospho-ERK levels.
• Learning the ABCs of Melanoma-Initiating Cells.
• Life isn't flat: taking cancer biology to the next dimension.
• Melanoma and the tumor microenvironment.
• Melanoma stem cells: the dark seed of melanoma.
• Old disease, new culprit: tumor stem cells in cancer.
• Peptides mimicking GD2 ganglioside elicit cellular, humoral and tumor-protective immune responses in mice.
• Salmonella typhimurium as a novel RNA interference vector for cancer gene therapy.
• Shared MHC class II-dependent melanoma ribosomal protein L8 identified by phage display.
• Targeting the stromal fibroblasts: a novel approach to melanoma therapy.
• The essential role of fibroblasts in esophageal squamous cell carcinoma-induced angiogenesis.
• The many faces of Notch signaling in skin-derived cells.
• Unraveling the mysteries of IGF-1 signaling in melanoma.
• [1st successful immunization of pancreas and colorectal carcinoma patients with CO17-1A-vaccine]
• [Not Available.]
• [POSTOPERATIVE EFFECTS OF CESAREAN SECTION.]
• [Stability of Teschen, HCC, ND and vaccinia viruses against 5 disinfectants]