Drug delivery to the brain has remained one of the most vexing problems in translational neuroscience research. This review rationalizes the strategies to target drugs to the brain. Factors such as the speed of intervention, the scale of intervention, the state of BBB, and the permissible risks, will all be critical in deciding how best to deliver drugs to a target site in the brain for a specific clinical situation.
Targeting the brain: rationalizing the novel methods of drug delivery to the central nervous system. Publishing Authors By Initials
Targeting the brain: rationalizing the novel methods of drug delivery to the central nervous system. Journal Published:
PUBLICATION TYPE: Review
Journal: Neurocritical care
VOLUME: 6
Page Numbers: 200-12
Journal Abbreviation:
ISSN: 1541-6933
DAY: 3
MONTH: 12
YEAR: 2007
Targeting the brain: rationalizing the novel methods of drug delivery to the central nervous system. Information
Number of References: 87
LANGUAGE: eng
NlmUniqueID: 101156086
Targeting the brain: rationalizing the novel methods of drug delivery to the central nervous system. Keywords Mesh Terms:
KEYWORDS: Time Factors
MESH TERMS: methods
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Grant and Affiliation Information for Targeting the brain: rationalizing the novel methods of drug delivery to the central nervous system.
AFFILIATION: Department of Anesthesiology, College of Physicians and Surgeons of Columbia University, 630 West 168th Street, P&S Box 46, New York, NY 10032, USA. sj121@columbia.edu
Country: United States
AGENCY: United States NCI
GRANT: R01 CA 89395
ACRONYM: CA
MEDLINETA: Neurocrit Care
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