Targeting invasion and egress: from tools to drugs?

Targeting invasion and egress: from tools to drugs? Research Abstract Details 

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Targeting invasion and egress: from tools to drugs? Abstract Text:

R E Morgan,K M Evans,S Patterson,F Catti,G E Ward,N J Westwood,

A recent resurgence in the use of compounds to study essential biological processes raises important questions concerning the link between fundamental research and drug development. This article discusses many of the issues involved, in the context of host cell invasion and egress by parasites of the Phylum Apicomplexa. In addition, an overview of the key steps in invasion and egress is provided with a particular emphasis on potential parasite protein drug targets.

Targeting invasion and egress: from tools to drugs? Publishing Authors By Initials

RE Morgan,KM Evans,S Patterson,F Catti,GE Ward,NJ Westwood,

For similar parasitic diseases: protozoan infections research abstracts see: parasitic diseases: protozoan infections research

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MEDLINE DATE:

Targeting invasion and egress: from tools to drugs? Journal Published:

PUBLICATION TYPE: Review

Journal: Current drug targets

VOLUME: 8

Page Numbers: 61-74

Journal Abbreviation:

ISSN: 1873-5592

DAY: 3

MONTH: Jan

YEAR: 2007

Targeting invasion and egress: from tools to drugs? Information

Number of References: 138

LANGUAGE: eng

NlmUniqueID: 100960531

Targeting invasion and egress: from tools to drugs? Keywords Mesh Terms:

KEYWORDS: Protozoan Infections

MESH TERMS: prevention & control

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Grant and Affiliation Information for Targeting invasion and egress: from tools to drugs?

AFFILIATION: School of Chemistry and Centre for Biomolecular Sciences, University of St Andrews, North Haugh, St. Andrews, Fife, Scotland, KY16 9ST, UK.

Country: Netherlands

AGENCY: United States NIAID

GRANT: AI054961

ACRONYM: AI

MEDLINETA: Curr Drug Targets

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