Targeted-ROI imaging in electron paramagnetic resonance imaging.

Targeted-ROI imaging in electron paramagnetic resonance imaging. Research Abstract Details 

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Targeted-ROI imaging in electron paramagnetic resonance imaging. Abstract Text:

Xiaochuan Pan,Dan Xia,Howard Halpern,

Electron paramagnetic resonance imaging (EPRI) is a technique that has been used for in vivo oxygen imaging of small animals. In continuous wave (CW) EPRI, the measurement can be interpreted as a sampled 4D Radon transform of the image function. The conventional filtered-backprojection (FBP) algorithm has been used widely for reconstructing images from full knowledge of the Radon transform acquired in CW EPRI. In practical applications of CW EPRI, one often is interested in information only in a region of interest (ROI) within the imaged subject. It is desirable to accurately reconstruct an ROI image only from partial knowledge of the Radon transform because acquisition of the partial data set can lead to considerable reduction of imaging time. The conventional FBP algorithm cannot, however, reconstruct accurate ROI images from partial knowledge of the Radon transform of even dimension. In this work, we describe two new algorithms, which are referred to as the backprojection filtration (BPF) and minimum-data filtered-backprojection (MDFBP) algorithms, for accurate ROI-image reconstruction from a partial Radon transform (or, truncated Radon transform) in CW EPRI. We have also performed numerical studies in the context of ROI-image reconstruction of a synthetic 2D image with density similar to that found in a small animal EPRI. This demonstrates both the inadequacy of the conventional FBP algorithm and the success of BPF and MDFBP algorithms in ROI reconstruction. The proposed ROI imaging approach promises a means to substantially reduce image acquisition time in CW EPRI.

Targeted-ROI imaging in electron paramagnetic resonance imaging. Publishing Authors By Initials

X Pan,D Xia,H Halpern,

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Targeted-ROI imaging in electron paramagnetic resonance imaging. Journal Published:

PUBLICATION TYPE: Research Support, U.S. Gov't,

Journal: Journal of magnetic resonance (San Diego, Calif. :

VOLUME: 187

Page Numbers: 66-77

Journal Abbreviation: J. Magn. Reson.

ISSN: 1090-7807

DAY: 23

MONTH: 02

YEAR: 2007

Targeted-ROI imaging in electron paramagnetic resonance imaging. Information

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LANGUAGE: eng

NlmUniqueID: 9707935

Targeted-ROI imaging in electron paramagnetic resonance imaging. Keywords Mesh Terms:

KEYWORDS: Phantoms, Imaging

MESH TERMS: methods

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Grant and Affiliation Information for Targeted-ROI imaging in electron paramagnetic resonance imaging.

AFFILIATION: Department of Radiology, The University of Chicago, Chicago, IL 60637-7117, USA.

Country: United States

AGENCY: United States NIBIB

GRANT: P41 EB 002034

ACRONYM: EB

MEDLINETA: J Magn Reson

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