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t(6;14)(q15;q32) in a patient with CD5+CD10+ diffuse large B-cell lymphoma.

t(6;14)(q15;q32) in a patient with CD5+CD10+ diffuse large B-cell lymphoma. Research Abstract Details 

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  • t(6;14)(q15;q32) in a patient with CD5+CD10+ diffuse large B-cell lymphoma. Abstract Text:

    miyuki hayamaMiyuki Hayama,nozomi niitsuNozomi Niitsu,masaaki higashiharaMasaaki Higashihara,hirokazu nakamineHirokazu Nakamine,ikuo miuraIkuo Miura,

    A 68-year-old man presented with systemic lymph node swelling. A biopsy specimen taken from the right cervical lymph node showed that the normal architecture was replaced by a diffuse proliferation of large lymphoid cells with large atypical nuclei. Immunohistochemical analysis showed that the atypical lymphoid cells were positive for CD5, CD10, CD20, CD79a, and Bcl2, and negative for CD3 and cyclin D1. A diagnosis of diffuse large B-cell lymphoma was made. Karyotypic findings included add(5)(q13), del(6)(q13), add(17)(p11), add(19)(p11), add(19)(p13), and t(6;14)(q15;q32). The serum lactate dehydrogenase level and indirect bilirubin level were slightly elevated. Elliptocytosis was observed in the peripheral blood, and a diagnosis of hereditary spherocytosis was made from the family history. Regarding CD5+CD10+ diffuse large B-cell lymphoma with a non-random chromosomal translocation of t(6;14)(q15;q32), studies on the mechanism of lymphomagenesis are needed.

    t(6;14)(q15;q32) in a patient with CD5+CD10+ diffuse large B-cell lymphoma. Publishing Authors By Initials

    m hayamaM Hayama,n niitsuN Niitsu,m higashiharaM Higashihara,h nakamineH Nakamine,i miuraI Miura,

    For similar pathological conditions, signs and symptoms: pathologic processes: chromosome aberrations: translocation, genetic research abstracts see: pathological conditions, signs and symptoms: pathologic processes: chromosome aberrations: translocation, genetic research

    PUBMED ID PMID:

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    t(6;14)(q15;q32) in a patient with CD5+CD10+ diffuse large B-cell lymphoma. Journal Published:

    PUBLICATION TYPE: Journal Article

    Journal: International journal of hematology

    VOLUME: 86

    Page Numbers: 147-9

    Journal Abbreviation: Int. J. Hematol.

    ISSN: 0925-5710

    DAY: 30

    MONTH: Aug

    YEAR: 2007

    t(6;14)(q15;q32) in a patient with CD5+CD10+ diffuse large B-cell lymphoma. Information

    Number of References:

    LANGUAGE: eng

    NlmUniqueID: 9111627

    t(6;14)(q15;q32) in a patient with CD5+CD10+ diffuse large B-cell lymphoma. Keywords Mesh Terms:

    KEYWORDS: Translocation, Genetic

    MESH TERMS: diagnosis

    Chemical & Substance for Abstract: t(6;14)(q15;q32) in a patient with CD5+CD10+ diffuse large B-cell lymphoma. Information

    Substance Name: Neprilysin

    Registry Number: EC 3.4.24.11

    Grant and Affiliation Information for t(6;14)(q15;q32) in a patient with CD5+CD10+ diffuse large B-cell lymphoma.

    AFFILIATION: Department of Hematology, Kitasato University, Sagamihara-shi, Kanagawa, Japan. mhayama@med.kitasato-u.ac.jp

    Country: United States

    United States Research PublicationUnited States Research Publication

    AGENCY:

    GRANT:

    ACRONYM:

    MEDLINETA: Int J Hematol

    REFSOURCE:

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    ACCESSION NUMBER:

    Number Hits: 0

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