T2 measurement of the human myocardium using a T2-prepared transient-state TrueFISP sequence.

T2 measurement of the human myocardium using a T2-prepared transient-state TrueFISP sequence. Research Abstract Details 

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T2 measurement of the human myocardium using a T2-prepared transient-state TrueFISP sequence. Abstract Text:

Teng-Yi Huang,Yi-Jui Liu,Alto Stemmer,Brigitte P Poncelet,

A fast and motion-insensitive technique suitable for myocardial BOLD contrast imaging is presented. The method, termed T2-TrueFISP, combines T2 magnetization preparation with steady-state free precession (SSFP) imaging for T2 relaxation mapping of the myocardium in healthy volunteers. The T2 contrast-to-noise ratio (CNR) was optimized with the use of transient-state TrueFISP readout and half-Fourier readout with linear phase encoding. Single-slice myocardial T2-weighted image was obtained within one heartbeat, and a single slice T2 map of the myocardium was obtained in under 5-7 s. A respiratory navigator-gating method was incorporated for serial measurements and signal averaging, with the subjects breathing freely. The mean myocardial T2 relaxation time measured in 12 healthy volunteers was 54 +/- 5.7 ms. Regional variations of T2 values across the myocardium were 7%. Temporal variations across serial T2 measurements in a transmural region covering approximately 0.5 cc of the left ventricular (LV) wall were 3.6% without signal averaging (number of excitations (NEX) = 1) and 1.7% with signal averaging (NEX = 10). According to our preliminary results, the T2-TrueFISP method is expected to provide a robust and sensitive tool for clinical application of myocardial BOLD contrast imaging.

T2 measurement of the human myocardium using a T2-prepared transient-state TrueFISP sequence. Publishing Authors By Initials

TY Huang,YJ Liu,A Stemmer,BP Poncelet,

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T2 measurement of the human myocardium using a T2-prepared transient-state TrueFISP sequence. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Magnetic resonance in medicine : official journal

VOLUME: 57

Page Numbers: 960-6

Journal Abbreviation:

ISSN: 0740-3194

DAY: 3

MONTH: May

YEAR: 2007

T2 measurement of the human myocardium using a T2-prepared transient-state TrueFISP sequence. Information

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LANGUAGE: eng

NlmUniqueID: 8505245

T2 measurement of the human myocardium using a T2-prepared transient-state TrueFISP sequence. Keywords Mesh Terms:

KEYWORDS: Phantoms, Imaging

MESH TERMS: methods

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Grant and Affiliation Information for T2 measurement of the human myocardium using a T2-prepared transient-state TrueFISP sequence.

AFFILIATION: Massachusetts General Hospital, MGH/MIT/HMS Athinoula A. Martinos Center for Biomedical Imaging, Charlestown, Massachusetts, USA. tyhuang@mail.ntust.edu.tw

Country: United States

AGENCY: United States NHLBI

GRANT: HL066489

ACRONYM: HL

MEDLINETA: Magn Reson Med

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