T-helper (th)1/th2 imbalance in the peripheral blood of dogs with malignant tumor.

T-helper (th)1/th2 imbalance in the peripheral blood of dogs with malignant tumor. Research Abstract Details 

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T-helper (th)1/th2 imbalance in the peripheral blood of dogs with malignant tumor. Abstract Text:

Yutaka Horiuchi,Asami Hanazawa,Yuko Nakajima,Yoko Nariai,Hideki Asanuma,Masato Kuwabara,Masayoshi Yukawa,Hiroshi Ito,Yutaka Horiuchi,Asami Hanazawa,Yuko Nakajima,Yoko Nariai,Hideki Asanuma,Masato Kuwabara,Masayoshi Yukawa,Hiroshi Ito,

T helper type 1 cell (Th1)/Th2 imbalance has been observed in a variety of pathological conditions, including malignant diseases. We evaluated the Th1/Th2 in peripheral blood Th cells by means of intracytoplasmic cytokine analysis in 11 dogs with advanced malignant tumor; four of them showed metastatic tumor. The percentage of Th1 was significantly lower and the percentage of Th2 was significantly higher in diseased dogs compared to healthy dogs. The percentage of Th1 in three patients with metastatic tumor was significantly lower than that in the patients with non-metastatic tumor. We conclude that the Th1/Th2 balance was polarized to Th2 in dogs with cancer.

T-helper (th)1/th2 imbalance in the peripheral blood of dogs with malignant tumor. Publishing Authors By Initials

Y Horiuchi,A Hanazawa,Y Nakajima,Y Nariai,H Asanuma,M Kuwabara,M Yukawa,H Ito,Y Horiuchi,A Hanazawa,Y Nakajima,Y Nariai,H Asanuma,M Kuwabara,M Yukawa,H Ito,

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T-helper (th)1/th2 imbalance in the peripheral blood of dogs with malignant tumor. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Microbiology and immunology

VOLUME: 51

Page Numbers: 1135-8

Journal Abbreviation: Microbiol. Immunol.

ISSN: 0385-5600

DAY: 26

MONTH: 11

YEAR: 2007

T-helper (th)1/th2 imbalance in the peripheral blood of dogs with malignant tumor. Information

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LANGUAGE: eng

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Grant and Affiliation Information for T-helper (th)1/th2 imbalance in the peripheral blood of dogs with malignant tumor.

AFFILIATION: Department of Veterinary Radiology, College of Bioresource Sciences, Nihon University.

Country: Japan

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MEDLINETA: Microbiol Immunol

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