Systolic blood pressure and systolic hypertension in adolescence of atomic bomb survivors exposed in utero.

Systolic blood pressure and systolic hypertension in adolescence of atomic bomb survivors exposed in utero. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Systolic blood pressure and systolic hypertension in adolescence of atomic bomb survivors exposed in utero. Abstract Text:

Eiji Nakashima,Masazumi Akahoshi,Kazuo Neriishi,Saeko Fujiwara,Eiji Nakashima,Masazumi Akahoshi,Kazuo Neriishi,Saeko Fujiwara,

Annual medical examinations were conducted during adolescence for the in utero clinical study sample subjects exposed prenatally to the atomic bombs in Hiroshima and Nagasaki. Systolic blood pressure and several anthropometric measurements were recorded during these examinations. For 1014 persons exposed in utero, two types of longitudinal analyses were performed, for a total of 7029 observations (6.93 observations per subject) of systolic blood pressure (continuous data) and systolic hypertension (binary data) for persons aged 9 to 19 years. Body mass index (BMI) and/or body weight were considered in the analyses as potential confounders. For the measurements of systolic blood pressure, the common dose effect was 2.09 mmHg per Gy and was significant (P = 0.017). The dose by trimester interaction was suggestive (P = 0.060). A significant radiation dose effect was found in the second trimester (P = 0.001), with an estimated 4.17 mmHg per Gy, but in the first and third trimesters, radiation dose effects were not significant (P > 0.50). For prevalence of systolic hypertension, the radiation dose effect was significant (P = 0.009); the odds ratio at 1 Gy was 2.23 [95% confidence interval (CI): 1.23, 4.04], and the dose by trimester interaction was not significant (P = 0.778). The dose response of systolic hypertension had no dose threshold, with a threshold point estimate of 0 Gy (95% CI: <0.0, 1.1 Gy). The dose response for systolic blood pressure was most pronounced in the second trimester, the most active organogenesis period for the organs relevant to blood pressure.

Systolic blood pressure and systolic hypertension in adolescence of atomic bomb survivors exposed in utero. Publishing Authors By Initials

E Nakashima,M Akahoshi,K Neriishi,S Fujiwara,E Nakashima,M Akahoshi,K Neriishi,S Fujiwara,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

Systolic blood pressure and systolic hypertension in adolescence of atomic bomb survivors exposed in utero. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Radiation research

VOLUME: 168

Page Numbers: 593-9

Journal Abbreviation: Radiat. Res.

ISSN: 0033-7587

DAY: 1

MONTH: Nov

YEAR: 2007

Systolic blood pressure and systolic hypertension in adolescence of atomic bomb survivors exposed in utero. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 401245

Systolic blood pressure and systolic hypertension in adolescence of atomic bomb survivors exposed in utero. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: Systolic blood pressure and systolic hypertension in adolescence of atomic bomb survivors exposed in utero. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Systolic blood pressure and systolic hypertension in adolescence of atomic bomb survivors exposed in utero.

AFFILIATION: Department of Statistics, Radiation Effects Research Foundation, Hiroshima 732-0815, Japan. nakasima@rerf.or.jp

Country: United States

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Radiat Res

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Systolic blood pressure and systolic hypertension in adolescence of atomic bomb survivors exposed in utero Related Publications

• A novel target-specific gene delivery system combining baculovirus and sequence-specific long interspersed nuclear elements.
• Amlodipine inhibits granulation tissue cell apoptosis through reducing calcineurin activity to attenuate postinfarction cardiac remodeling.
• An Arabidopsis thaliana high-affinity molybdate transporter required for efficient uptake of molybdate from soil.
• Cell-type specificity of the expression of Os BOR1, a rice efflux boron transporter gene, is regulated in response to boron availability for efficient boron uptake and xylem loading.
• Diet during adolescence is a trigger for subsequent development of dysmenorrhea in young women.
• Effects of benidipine and some other calcium channel blockers on the prognosis of patients with vasospastic angina. Cohort study with evaluation of the ergonovine coronary spasm induction test.
• Extinction-effective population index: incorporating life-history variations in population viability analysis.
• Extrahepatic manifestations in transgenic mice of osteopontin in hepatocytes-A clue to advent of pathological state in various organs of chronic hepatitis C patients.
• FDTD Computation of Temperature Elevation in Human Body for RF Far-Field Exposure.
• Immunocytochemical studies on the distribution pattern of daunomycin in rat gastrointestinal tract.
• In vivo hepatocyte growth factor gene transfer reduces myocardial ischemia-reperfusion injury through its multiple actions.
• Increased cytoprotective function in the liver of transgenic mice expressing osteopontin in hepatocytes.
• Induction of ischemic tolerance in rat liver via reduced nicotinamide adenine dinucleotide phosphate oxidase in Kupffer cells.
• Involvement of ERK/MAPK in regulation of diapause intensity in the false melon beetle, Atrachya menetriesi.
• Involvement of GABA(A) receptors in the neuroprotective effect of theanine on focal cerebral ischemia in mice.
• Ligand specificity of MobR, a transcriptional regulator for the 3-hydroxybenzoate hydroxylase gene of Comamonas testosteroni KH122-3s.
• Melanogenesis inhibition by an oolong tea extract in b16 mouse melanoma cells and UV-induced skin pigmentation in brownish guinea pigs.
• Multipotent epithelial cells in the process of regeneration and asexual reproduction in colonial tunicates.
• NMR metabolic profiling combined with two-step principal component analysis for toxin-induced diabetes model rat using urine.
• Nodal regulates neural tube formation in the Ciona intestinalis embryo.
• Plants tolerant of high boron levels.
• Pravastatin reduces myocardial infarct size via increasing protein kinase C-dependent nitric oxide, decreasing oxyradicals and opening the mitochondrial adenosine triphosphate-sensitive potassium channels in rabbits.
• Renoprotective effect of the addition of losartan to ongoing treatment with an Angiotensin converting enzyme inhibitor in type-2 diabetic patients with nephropathy.
• Secretory IgA level in pharyngeal mucous of infants with different feeding methods at the age of four to eight weeks.
• Serum response factor: master regulator of the actin cytoskeleton and contractile apparatus.
• Stimulation by glutamine and proline of HGF production in hepatic stellate cells.
• Systolic blood pressure and systolic hypertension in adolescence of atomic bomb survivors exposed in utero.
• Two-stage formation model and helicity of gold nanowires.
• Weekly paclitaxel and carboplatin against advanced transitional cell cancer after failure of a platinum-based regimen.
• [Mechanisms of symptoms in functional dyspepsia]