Systemic Risk Score Evaluation in Ischemic Stroke Patients (SCALA) : A prospective cross sectional study in 85 German stroke units.

Systemic Risk Score Evaluation in Ischemic Stroke Patients (SCALA) : A prospective cross sectional study in 85 German stroke units. Research Abstract Details 

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Systemic Risk Score Evaluation in Ischemic Stroke Patients (SCALA) : A prospective cross sectional study in 85 German stroke units. Abstract Text:

C Weimar,M Goertler,J ,E B Ringelstein,H Darius,D G Nabavi,I-H Kim,K Theobald,H-C Diener, ,Christian Weimar,Michael Goertler,Joachim Röther,E Bernd Ringelstein,Harald Darius,Darius Günther Nabavi,In-Ha Kim,Karlheinz Theobald,Han-Christoph Diener, ,Christian Weimar,Michael Goertler,Joachim ,E Bernd Ringelstein,Harald Darius, Nabavi,In-Ha Kim,Karlheinz Theobald,Han-Christoph Diener, ,

BACKGROUND AND PURPOSE : Stratification of patients with transient ischemic attack (TIA) or ischemic stroke (IS) by risk of recurrent stroke can contribute to optimized secondary prevention. We therefore aimed to assess cardiovascular risk factor profiles of consecutive patients hospitalized with TIA/IS to stratify the risk of recurrent stroke according to the Essen Stroke Risk Score (ESRS) and of future cardiovascular events according to the ankle brachial index (ABI) as a marker of generalized atherosclerosis METHODS : In this cross-sectional observational study, 85 neurological stroke units throughout Germany documented cardiovascular risk factor profiles of 10 consecutive TIA/IS patients on standardized questionnaires. Screening for PAD was done with Doppler ultrasonography to calculate the ABI. RESULTS : A total of 852 patients (57% men) with a mean age of 67+/-12.4 years were included of whom 82.9 % had IS. The median National Institutes of Health stroke sum score was 4 (TIA: 1). Arterial hypertension was reported in 71%, diabetes mellitus in 26%, clinical PAD in 10%, and an ABI /= 3 was observed in 58%, which in two previous retrospective analyses corresponded to a recurrent stroke risk of >/= 4%/year. The correlation between the ESRS and the ABI was low (r = 0.21). CONCLUSION : A high proportion of patients had asymptomatic atherosclerotic disease and a considerable risk of recurrent stroke according to the ABI and ESRS category. The prognostic accuracy as well as the potential benefit of various risk stratification scores in secondary stroke prevention require validation in a larger prospective study.

Systemic Risk Score Evaluation in Ischemic Stroke Patients (SCALA) : A prospective cross sectional study in 85 German stroke units. Publishing Authors By Initials

C Weimar,M Goertler,J ,EB Ringelstein,H Darius,DG Nabavi,IH Kim,K Theobald,HC Diener, ,C Weimar,M Goertler,J Röther,EB Ringelstein,H Darius,DG Nabavi,IH Kim,K Theobald,HC Diener, ,C Weimar,M Goertler,J ,EB Ringelstein,H Darius,DG Nabavi,IH Kim,K Theobald,HC Diener, ,

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Systemic Risk Score Evaluation in Ischemic Stroke Patients (SCALA) : A prospective cross sectional study in 85 German stroke units. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Journal of neurology

VOLUME: 254

Page Numbers: 1562-8

Journal Abbreviation: J. Neurol.

ISSN: 0340-5354

DAY: 3

MONTH: 08

YEAR: 2007

Systemic Risk Score Evaluation in Ischemic Stroke Patients (SCALA) : A prospective cross sectional study in 85 German stroke units. Information

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LANGUAGE: eng

NlmUniqueID: 423161

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AFFILIATION: Dept. of Neurology, University of Duisburg-Essen, Hufelandstrasse 55, 45122, Essen, Germany, h.diener@uni-essen.de.

Country: Germany

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MEDLINETA: J Neurol

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