[Systemic influence after an island flap with venous congestion-reperfusion injury]

[Systemic influence after an island flap with venous congestion-reperfusion injury] Research Abstract Details 

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[Systemic influence after an island flap with venous congestion-reperfusion injury] Abstract Text:

Jing-min Cao,Kai-hua Lu,Biao Wang,Shu-zhong Guo,

OBJECTIVE: To investigate the systemic influence after an island flap with venous congestion-reperfusion. METHODS: An island flap was formed in a Rat model. The vein in the pedicle was clamped for 2 hours, 6 hours and 10 hours and released. The ear microcirculation, levels of TNF alpha and IL-10 were measured, and the neutrophils sequestration in tissues were counted. The vascular structure of the lung and intestine were evaluated. RESULTS: There were significant changes in the ear microcirculation, neutrophils sequestration of the lung and the intestine in the 2 hours, 6 hours and 10 hours groups, and became more serious by the time increasing. The TNF alpha level reached in maximum at 1 hour after the reperfusion, while the IL-10 became to the lowest level at 3 hours after the reperfusion. However, the TNF alpha and IL-10 levels were significant high in the 6 hour and 10 hours groups, compared with the 2 hours group and the control, but there was no differences between the2 hours group and the control. CONCLUSIONS: Venous congestion-reperfusion of flap could injury the remote organs such as lung, intestinal etc. The injury could be more serious with the time increasing.

[Systemic influence after an island flap with venous congestion-reperfusion injury] Publishing Authors By Initials

JM Cao,KH Lu,B Wang,SZ Guo,

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[Systemic influence after an island flap with venous congestion-reperfusion injury] Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Zhonghua zheng xing wai ke za zhi = Zhonghua zheng

VOLUME: 19

Page Numbers: 21-3

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ISSN: 1009-4598

DAY: 3

MONTH: Jan

YEAR: 2003

[Systemic influence after an island flap with venous congestion-reperfusion injury] Information

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LANGUAGE: chi

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Grant and Affiliation Information for [Systemic influence after an island flap with venous congestion-reperfusion injury]

AFFILIATION: Xijing Hospital, Fourth Military Medical University, Xi'an 710032, China.

Country: China

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MEDLINETA: Zhonghua Zheng Xing Wai Ke Za

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