Systematic assessment of training-induced changes in corticospinal output to hand using frameless stereotaxic transcranial magnetic stimulation.

Systematic assessment of training-induced changes in corticospinal output to hand using frameless stereotaxic transcranial magnetic stimulation. Research Abstract Details 

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Systematic assessment of training-induced changes in corticospinal output to hand using frameless stereotaxic transcranial magnetic stimulation. Abstract Text:

Jeffrey A Kleim,Erin D Kleim,Steven C Cramer,Jeffrey A Kleim,Erin D Kleim,Steven C Cramer,

Measuring changes in the characteristics of corticospinal output has become a critical part of assessing the impact of motor experience on cortical organization in both the intact and injured human brain. In this protocol we describe a method for systematically assessing training-induced changes in corticospinal output that integrates volumetric anatomical MRI with transcranial magnetic stimulation (TMS). A TMS coil is sited to a target grid superimposed onto a 3D MRI of cortex using a stereotaxic neuronavigation system. Subjects are then required to exercise the first dorsal interosseus (FDI) muscle on two different tasks for a total of 30 min. The protocol allows for reliably and repeatedly detecting changes in corticospinal output to FDI muscle in response to brief periods of motor training.

Systematic assessment of training-induced changes in corticospinal output to hand using frameless stereotaxic transcranial magnetic stimulation. Publishing Authors By Initials

JA Kleim,ED Kleim,SC Cramer,JA Kleim,ED Kleim,SC Cramer,

For similar diagnosis: diagnostic techniques and procedures: diagnostic techniques, neurological: transcranial magnetic stimulation research abstracts see: diagnosis: diagnostic techniques and procedures: diagnostic techniques, neurological: transcranial magnetic stimulation research

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Systematic assessment of training-induced changes in corticospinal output to hand using frameless stereotaxic transcranial magnetic stimulation. Journal Published:

PUBLICATION TYPE: Research Support, N.I.H., Extr

Journal: Nature protocols

VOLUME: 2

Page Numbers: 1675-84

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ISSN: 1750-2799

DAY: 3

MONTH: 12

YEAR: 2007

Systematic assessment of training-induced changes in corticospinal output to hand using frameless stereotaxic transcranial magnetic stimulation. Information

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LANGUAGE: eng

NlmUniqueID: 101284307

Systematic assessment of training-induced changes in corticospinal output to hand using frameless stereotaxic transcranial magnetic stimulation. Keywords Mesh Terms:

KEYWORDS: Transcranial Magnetic Stimulation

MESH TERMS: methods

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Grant and Affiliation Information for Systematic assessment of training-induced changes in corticospinal output to hand using frameless stereotaxic transcranial magnetic stimulation.

AFFILIATION: Brain Rehabilitation Research Center, Malcom Randall VA Hospital, 1601 SW Archer Road, Gainesville, Florida 32608, USA. jkleim@ufl.edu

Country: England

AGENCY: United States NINDS

GRANT: NS-45563

ACRONYM: NS

MEDLINETA: Nat Protoc

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