Synthesis of pyridinoline during in vitro aging of bone collagen.

Synthesis of pyridinoline during in vitro aging of bone collagen. Research Abstract Details 

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Synthesis of pyridinoline during in vitro aging of bone collagen. Abstract Text:

A Uchiyama,T Inoue,D Fujimoto,

Pyridinoline is a non-reducible crosslink of collagen. The changes in the content of this crosslink during in vitro aging of bone collagen were studied. The pyridinoline content of bone collagen of 6-week-old chick was very low. When the collagen was incubated with physiological saline in air at 37 degrees C, the pyridinoline content increased markedly. After 6 weeks, the content reached the same level as that of the adult. The synthesis of pyridinoline was inhibited when air was excluded. The in vitro aged collagen was less susceptible to pepsin than the untreated collagen. The results indicate that pyridinoline is one of the mature crosslinks of collagen and plays a role in the stabilization of collagen fibers.

Synthesis of pyridinoline during in vitro aging of bone collagen. Publishing Authors By Initials

A Uchiyama,T Inoue,D Fujimoto,

For similar macromolecular substances: polymers: biopolymers: collagen research abstracts see: macromolecular substances: polymers: biopolymers: collagen research

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Synthesis of pyridinoline during in vitro aging of bone collagen. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Journal of biochemistry

VOLUME: 90

Page Numbers: 1795-8

Journal Abbreviation: J. Biochem.

ISSN: 0021-924X

DAY: 19

MONTH: Dec

YEAR: 1981

Synthesis of pyridinoline during in vitro aging of bone collagen. Information

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LANGUAGE: eng

NlmUniqueID: 376600

Synthesis of pyridinoline during in vitro aging of bone collagen. Keywords Mesh Terms:

KEYWORDS: Collagen

MESH TERMS: metabolism

Chemical & Substance for Abstract: Synthesis of pyridinoline during in vitro aging of bone collagen. Information

Substance Name: Collagen

Registry Number: 9007-34-5

Grant and Affiliation Information for Synthesis of pyridinoline during in vitro aging of bone collagen.

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Country: JAPAN

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MEDLINETA: J Biochem

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