Synthesis of D-labeled naphthyliodoacetamide and application to quantitative peptide analysis by isotope differential mass spectrometry.

Synthesis of D-labeled naphthyliodoacetamide and application to quantitative peptide analysis by isotope differential mass spectrometry. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Synthesis of D-labeled naphthyliodoacetamide and application to quantitative peptide analysis by isotope differential mass spectrometry. Abstract Text:

Satomi Niwayama,Sadamu Kurono,Hanjoung Cho,Hiroyuki Matsumoto,

D-labeled and -unlabeled N-beta-naphthyliodoacetamides have been synthesized for specific modification of the sulfhydryl groups of cysteine residues in proteins or peptides, and have been applied to quantitative analysis of several peptides. A combination of these reagents, coupled with mass spectrometry, is anticipated to serve as a useful tool for quantitative analysis of peptides and hence proteins.

Synthesis of D-labeled naphthyliodoacetamide and application to quantitative peptide analysis by isotope differential mass spectrometry. Publishing Authors By Initials

S Niwayama,S Kurono,H Cho,H Matsumoto,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

Synthesis of D-labeled naphthyliodoacetamide and application to quantitative peptide analysis by isotope differential mass spectrometry. Journal Published:

PUBLICATION TYPE: Research Support, N.I.H., Extr

Journal: Bioorganic & medicinal chemistry letters

VOLUME: 16

Page Numbers: 6054-7

Journal Abbreviation: Bioorg. Med. Chem. Lett.

ISSN: 0960-894X

DAY: 18

MONTH: 09

YEAR: 2006

Synthesis of D-labeled naphthyliodoacetamide and application to quantitative peptide analysis by isotope differential mass spectrometry. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 9107377

Synthesis of D-labeled naphthyliodoacetamide and application to quantitative peptide analysis by isotope differential mass spectrometry. Keywords Mesh Terms:

KEYWORDS: Spectrometry, Mass, Matrix-Assisted Lase

MESH TERMS: analysis

Chemical & Substance for Abstract: Synthesis of D-labeled naphthyliodoacetamide and application to quantitative peptide analysis by isotope differential mass spectrometry. Information

Substance Name: Iodoacetamide

Registry Number: 144-48-9

Grant and Affiliation Information for Synthesis of D-labeled naphthyliodoacetamide and application to quantitative peptide analysis by isotope differential mass spectrometry.

AFFILIATION: Department of Chemistry and Biochemistry, Texas Tech University, Box 41061, Lubbock, TX 79409-1061, USA. satomi.niwayama@ttu.edu <satomi.niwayama@ttu.edu>

Country: England

AGENCY: United States NCRR

GRANT: RR17703

ACRONYM: RR

MEDLINETA: Bioorg Med Chem Lett

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Synthesis of D-labeled naphthyliodoacetamide and application to quantitative peptide analysis by isotope differential mass spectrometry Related Publications

• A Third Locus for Eosinophilia on Chromosome 1 of the MES Rats.
• Anticariogenic effect of fluoride-releasing elastomers in orthodontic patients.
• Complement 3 is involved in changing the phenotype of human glomerular mesangial cells.
• Crystal structure, mesomorphic and emission properties of liquid crystals having a 7-(diethylamino)-3-phenylcoumarin core.
• Dental-skeletal dimensions in growing individuals with variations in the lower facial height.
• Durability of endourologic skills: two-year follow-up study.
• Effects of IL-6 and soluble IL-6 receptor on the expression of cartilage matrix proteins in human chondrocytes.
• Epistasis between hyperglycemic QTLs revealed in a double congenic of the OLETF rat.
• Estrogen promotes early osteoblast differentiation and inhibits adipocyte differentiation in mouse bone marrow stromal cell lines that express estrogen receptor (ER) alpha or beta.
• Fundamental aspects of hypogonadism in the aging male.
• Glossopharyngeal neuralgia due to an epidermoid tumour in the cerebellopontine angle.
• Mammographic x-ray spectra measured by Compton spectroscopy using a high resolution Schottky CdTe detector.
• Microbubble-induced increase in ablation of liver tumors by high-intensity focused ultrasound.
• N-[2-(m-methoxyphenyl)ethyl]-N-ethyl-2-(1-pyrrolidinyl)ethylamine (UMB 116) is a novel antagonist for cocaine-induced effects.
• Novel eye-specific calmodulin methylation characterized by protein mapping in Drosophila melanogaster.
• Novel sigma (sigma) receptor agonists produce antidepressant-like effects in mice.
• Optic nerve decompression for orbitofrontal fibrous dysplasia.
• Perforation of Meckel's diverticulum manifesting as aseptic peritonitis in a neonate: report of a case.
• Proteomics study of neuropathic and nonneuropathic dorsal root ganglia: altered protein regulation following segmental spinal nerve ligation injury.
• Radiofrequency ablation and cryoablation of renal tumours.
• Rapid detection of human herpesvirus 8 DNA using loop-mediated isothermal amplification.
• Segmental alveolar distraction for the correction of unilateral open-bite caused by multiple ankylosed teeth: A case report.
• Sex pheromone production in the silkworm, Bombyx mori, is mediated by store-operated Ca2+ channels.
• Somatostatin inhibits the excitability of rat small-diameter trigeminal ganglion neurons that innervate nasal mucosa and project to the upper cervical dorsal horn via activation of somatostatin 2a receptor.
• Synthesis of D-labeled naphthyliodoacetamide and application to quantitative peptide analysis by isotope differential mass spectrometry.
• The Bombyx mori sex pheromone biosynthetic pathway is not mediated by cAMP.
• The Dugesia ryukyuensis database as a molecular resource for studying switching of the reproductive system.
• Therapy with bortezomib plus dexamethasone induces osteoblast activation in responsive patients with multiple myeloma.
• [Evaluation of the accuracy of line spread function (LSF) and point spread function (PSF) measured in the computed tomography.]
• [Phosphatonin]