Synthesis of C-11 modified mifepristone analog libraries.

Synthesis of C-11 modified mifepristone analog libraries. Research Abstract Details 

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Synthesis of C-11 modified mifepristone analog libraries. Abstract Text:

Gregory L Hamilton,Bradley J Backes,

Substitution of the C-11 aniline of mifepristone can provide compounds with altered pharmacokinetic and pharmacodynamic (PK/PD) profiles that may find use for new indications. The development of new steroid intermediates and specialized library synthesis methods were required to enable the efficient preparation of structurally complex C-11 modified mifepristone analogs.

Synthesis of C-11 modified mifepristone analog libraries. Publishing Authors By Initials

GL Hamilton,BJ Backes,

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Synthesis of C-11 modified mifepristone analog libraries. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Molecular diversity

VOLUME: 11

Page Numbers: 107-11

Journal Abbreviation: Mol. Divers.

ISSN: 1381-1991

DAY: 6

MONTH: 06

YEAR: 2007

Synthesis of C-11 modified mifepristone analog libraries. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 9516534

Synthesis of C-11 modified mifepristone analog libraries. Keywords Mesh Terms:

KEYWORDS: Peptide Library

MESH TERMS: chemistry

Chemical & Substance for Abstract: Synthesis of C-11 modified mifepristone analog libraries. Information

Substance Name: Mifepristone

Registry Number: 84371-65-3

Grant and Affiliation Information for Synthesis of C-11 modified mifepristone analog libraries.

AFFILIATION: Metabolic Disease Research, Global Pharmaceutical Research and Development, Abbott Laboratories, 100 Abbott Park Road, Abbott Park, IL 60064-6098, USA.

Country: Netherlands

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MEDLINETA: Mol Divers

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