Synthesis of beta-lactones: a highly active and selective catalyst for epoxide carbonylation.

Synthesis of beta-lactones: a highly active and selective catalyst for epoxide carbonylation. Research Abstract Details 

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Synthesis of beta-lactones: a highly active and selective catalyst for epoxide carbonylation. Abstract Text:

Yutan D Y L Getzler,Viswanath Mahadevan,Emil B Lobkovsky,Geoffrey W Coates,

A new highly active and selective catalyst for the synthesis of beta-lactones from CO and epoxides is reported. The catalyst, [(N,N'-bis(3,5-di-tert-butylsalicylidene) phenylenediamino)Al(THF)2][Co(CO)4] ([(salph)Al(THF)2][Co(CO)4]) is easily prepared from the corresponding (salph)AlCl and NaCo(CO)4. At 50 degrees C and 880 psi of CO, the catalyst (1 mol %) carbonylates epoxides such as propylene oxide, 1-butene oxide, epichlorohydrin, and isobutylene oxide to the lactones beta-butyrolactone, beta-valerolactone, gamma-chloro-beta-butyrolactone, and beta-methyl-beta-butyrolactone in high yield. (R)-Propylene oxide was carbonylated to (R)-beta-butyrolactone with retention of stereochemistry.

Synthesis of beta-lactones: a highly active and selective catalyst for epoxide carbonylation. Publishing Authors By Initials

YD Getzler,V Mahadevan,EB Lobkovsky,GW Coates,

For similar macromolecular substances: polymers: polyesters research abstracts see: macromolecular substances: polymers: polyesters research

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Synthesis of beta-lactones: a highly active and selective catalyst for epoxide carbonylation. Journal Published:

PUBLICATION TYPE: Research Support, U.S. Gov't,

Journal: Journal of the American Chemical Society

VOLUME: 124

Page Numbers: 1174-5

Journal Abbreviation: J. Am. Chem. Soc.

ISSN: 0002-7863

DAY: 20

MONTH: Feb

YEAR: 2002

Synthesis of beta-lactones: a highly active and selective catalyst for epoxide carbonylation. Information

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LANGUAGE: eng

NlmUniqueID: 7503056

Synthesis of beta-lactones: a highly active and selective catalyst for epoxide carbonylation. Keywords Mesh Terms:

KEYWORDS: Polyesters

MESH TERMS: chemistry

Chemical & Substance for Abstract: Synthesis of beta-lactones: a highly active and selective catalyst for epoxide carbonylation. Information

Substance Name: Cobalt

Registry Number: 7440-48-4

Grant and Affiliation Information for Synthesis of beta-lactones: a highly active and selective catalyst for epoxide carbonylation.

AFFILIATION: Department of Chemistry and Chemical Biology, Baker Laboratory, Cornell University, Ithaca, New York 14853, USA.

Country: United States

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MEDLINETA: J Am Chem Soc

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