[reaction: see text] Microwave-promoted, cobalt-catalyzed intramolecular [2 + 2 + 2] cyclizations of dialkynylnitriles successfully gave 5,6,7,8-tetrahydro-1,6-naphthyridines. The efficient synthesis of these relatively simple, yet rarely addressed heterocycles enabled the preparation of a collection of these compounds.
Synthesis of 5,6,7,8-tetrahydro-1,6-naphthyridines and related heterocycles by cobalt-catalyzed [2 + 2 + 2] cyclizations. Publishing Authors By Initials
Synthesis of 5,6,7,8-tetrahydro-1,6-naphthyridines and related heterocycles by cobalt-catalyzed [2 + 2 + 2] cyclizations. Journal Published:
PUBLICATION TYPE: Research Support, N.I.H., Extr
Journal: Organic letters
VOLUME: 9
Page Numbers: 393-6
Journal Abbreviation: Org. Lett.
ISSN: 1523-7060
DAY: 1
MONTH: Feb
YEAR: 2007
Synthesis of 5,6,7,8-tetrahydro-1,6-naphthyridines and related heterocycles by cobalt-catalyzed [2 + 2 + 2] cyclizations. Information
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LANGUAGE: eng
NlmUniqueID: 100890393
Synthesis of 5,6,7,8-tetrahydro-1,6-naphthyridines and related heterocycles by cobalt-catalyzed [2 + 2 + 2] cyclizations. Keywords Mesh Terms:
KEYWORDS: Stereoisomerism
MESH TERMS: chemistry
Chemical & Substance for Abstract: Synthesis of 5,6,7,8-tetrahydro-1,6-naphthyridines and related heterocycles by cobalt-catalyzed [2 + 2 + 2] cyclizations. Information
Substance Name: Cobalt
Registry Number: 7440-48-4
Grant and Affiliation Information for Synthesis of 5,6,7,8-tetrahydro-1,6-naphthyridines and related heterocycles by cobalt-catalyzed [2 + 2 + 2] cyclizations.
AFFILIATION: Department of Chemistry and the Center for Methodology and Library Development, Boston University, Boston, Massachusetts 02215, USA.
Country: United States
AGENCY: United States NIGMS
GRANT: P50 GM067041
ACRONYM: GM
MEDLINETA: Org Lett
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Synthesis of 5,6,7,8-tetrahydro-1,6-naphthyridines and related heterocycles by cobalt-catalyzed 2 + 2 + 2 cyclizations Related Publications