Synthesis of (+/-)-epi-stegobinone utilizing silacyclopropanes as synthetic intermediates.

Synthesis of (+/-)-epi-stegobinone utilizing silacyclopropanes as synthetic intermediates. Research Abstract Details 

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Synthesis of (+/-)-epi-stegobinone utilizing silacyclopropanes as synthetic intermediates. Abstract Text:

Stacie A Calad,Jelena Cirakovi?,K A Woerpel,

The synthesis of (+/-)-1'-epi-stegobinone has been accomplished in ten steps and 17% overall yield from a recently reported silacyclopropane-derived diol. All stereocenters of the final product were established relative to the stereochemistry of the initial silacyclopropane. This synthesis represents the first time silacyclopropane reactivity has been employed in a target-directed synthesis.

Synthesis of (+/-)-epi-stegobinone utilizing silacyclopropanes as synthetic intermediates. Publishing Authors By Initials

SA Calad,J Cirakovi?,KA Woerpel,

For similar natural sciences: chemistry: chemistry, organic: isomerism: stereoisomerism research abstracts see: natural sciences: chemistry: chemistry, organic: isomerism: stereoisomerism research

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Synthesis of (+/-)-epi-stegobinone utilizing silacyclopropanes as synthetic intermediates. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: The Journal of organic chemistry

VOLUME: 72

Page Numbers: 1027-30

Journal Abbreviation: J. Org. Chem.

ISSN: 0022-3263

DAY: 2

MONTH: Feb

YEAR: 2007

Synthesis of (+/-)-epi-stegobinone utilizing silacyclopropanes as synthetic intermediates. Information

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LANGUAGE: eng

NlmUniqueID: 2985193

Synthesis of (+/-)-epi-stegobinone utilizing silacyclopropanes as synthetic intermediates. Keywords Mesh Terms:

KEYWORDS: Stereoisomerism

MESH TERMS: chemistry

Chemical & Substance for Abstract: Synthesis of (+/-)-epi-stegobinone utilizing silacyclopropanes as synthetic intermediates. Information

Substance Name: Silicon

Registry Number: 7440-21-3

Grant and Affiliation Information for Synthesis of (+/-)-epi-stegobinone utilizing silacyclopropanes as synthetic intermediates.

AFFILIATION: Department of Chemistry, University of California, Irvine, California 92697-2025, USA.

Country: United States

AGENCY: United States NIGMS

GRANT: GM-54909

ACRONYM: GM

MEDLINETA: J Org Chem

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