Synthesis and biological activity of mixed ligand dioxouranium(VI) and thorium(IV) complexes.

Synthesis and biological activity of mixed ligand dioxouranium(VI) and thorium(IV) complexes. Research Abstract Details 

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Synthesis and biological activity of mixed ligand dioxouranium(VI) and thorium(IV) complexes. Abstract Text:

Ganesh A Thakur,Shrikant V Athlekar,Sanjiv R Dharwadkar,Manzoor M Shaikh,

Mixed ligand complexes of dioxouranium(VI) and thorium(IV) in the proportion 1:1:1 and 1:2:1 have been synthesized using 8-hydroxyquinoline as a primary ligand and L-proline and 4-hydroxy-L-proline as secondary ligands, respectively. The metal complexes have been characterized on the basis of elemental analysis, molar conductance, magnetic, spectral and thermal studies. The molar conductance studies of the complexes in DMF at 10(-3) M concentrations indicate their non-electrolytic nature. Room temperature magnetic susceptibility measurements revealed diamagnetic nature of the complexes. Electronic absorption spectra of the complexes show intra-ligand and charge transfer transitions, respectively. The thermal analysis data of the complexes indicates the presence of a coordinated water molecule/molecules. The tube dilution method has been used to study the antibacterial activity of the complexes against the pathogenic bacteria Staphylococcus aureus and Escherichia coli. The results have been compared against those of control tetracycline, which was screened simultaneously. The complexes have been screened for in vitro cytotoxicity (IC50) studies against Ehrlich ascites cells and Dalton's lymphoma ascites cells, respectively.

Synthesis and biological activity of mixed ligand dioxouranium(VI) and thorium(IV) complexes. Publishing Authors By Initials

GA Thakur,SV Athlekar,SR Dharwadkar,MM Shaikh,

For similar inorganic chemicals: elements: actinoid series elements: uranium research abstracts see: inorganic chemicals: elements: actinoid series elements: uranium research

PUBMED ID PMID:

MEDLINE DATE: 2007 Jan-Feb

Synthesis and biological activity of mixed ligand dioxouranium(VI) and thorium(IV) complexes. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Acta poloniae pharmaceutica

VOLUME: 64

Page Numbers: 9-15

Journal Abbreviation:

ISSN: 0001-6837

DAY: 30

MONTH: 11

YEAR: 2007

Synthesis and biological activity of mixed ligand dioxouranium(VI) and thorium(IV) complexes. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 2985167

Synthesis and biological activity of mixed ligand dioxouranium(VI) and thorium(IV) complexes. Keywords Mesh Terms:

KEYWORDS: Uranium

MESH TERMS: pharmacology

Chemical & Substance for Abstract: Synthesis and biological activity of mixed ligand dioxouranium(VI) and thorium(IV) complexes. Information

Substance Name: Uranium

Registry Number: 7440-61-1

Grant and Affiliation Information for Synthesis and biological activity of mixed ligand dioxouranium(VI) and thorium(IV) complexes.

AFFILIATION: Department of Chemistry, Mahatma Phule A. S. C. College, Panvel, Dist. Raigad (Maharashtra) 410206, India.

Country: Poland

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MEDLINETA: Acta Pol Pharm

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