Symptomatic acute reactive arthritis after an outbreak of salmonella.

Symptomatic acute reactive arthritis after an outbreak of salmonella. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Symptomatic acute reactive arthritis after an outbreak of salmonella. Abstract Text:

OBJECTIVE: In 2005, 592 individuals in Ontario developed acute gastroenteritis, predominantly after consuming bean sprouts contaminated with Salmonella enteritidis. Salmonella is a known trigger of reactive arthritis (ReA). We describe the population affected by the Salmonella outbreak in terms of clinical presentation of self-reported arthritic symptoms and HLA-B27 genotyping. METHODS: Subjects were mailed a questionnaire, which assessed symptoms consistent with ReA. Subsequently, subjects were asked to submit saliva samples, which were analyzed for HLA-B27. Simple descriptive statistics were performed for analysis of survey responses, and the genetic component was analyzed by chi-square or Fisher's exact tests. RESULTS: Most respondents were female (71.3%), with a mean age of 46.0 years. The mean duration of diarrhea symptoms was 16.5 days. 62.5% of respondents reported extraintestinal symptoms that were consistent with ReA. The most commonly reported features were joint pain, swelling or stiffness (46.2%), stiffness > 30 min (35.6%), ocular symptoms (24.0%), and visibly swollen joints (19.2%). Subjects with Salmonella infection had a similar incidence of HLA-B27, regardless of whether they developed symptoms consistent with ReA or not. Notably, HLA-B27 was present more frequently in those who developed Salmonella infection than in healthy controls (OR 3.0). CONCLUSION: The study, one of the largest for a dysenteric outbreak, revealed a high event rate of self-reported symptoms consistent with ReA in those infected with Salmonella. Our results showed that HLA-B27 may have rendered individuals more susceptible to Salmonella infection, but did not contribute to the development of symptoms consistent with ReA after infection. We note that the methods used in this study, including self-report, are not ideal for diagnosis of inflammatory arthritis. However, given the rarity of large outbreaks of Salmonella, the study adds valuable knowledge about the course of ReA.

Symptomatic acute reactive arthritis after an outbreak of salmonella. Publishing Authors By Initials

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

Symptomatic acute reactive arthritis after an outbreak of salmonella. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: The Journal of rheumatology

VOLUME: 35

Page Numbers: 1599-602

Journal Abbreviation: J. Rheumatol.

ISSN: 0315-162X

DAY: 1

MONTH: 06

YEAR: 2008

Symptomatic acute reactive arthritis after an outbreak of salmonella. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 7501984

Symptomatic acute reactive arthritis after an outbreak of salmonella. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: Symptomatic acute reactive arthritis after an outbreak of salmonella. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Symptomatic acute reactive arthritis after an outbreak of salmonella.

AFFILIATION: From the Toronto Western Hospital, University Health Network, Toronto; and Public Health Division, Ministry of Health and Long Term Care, Toronto, Ontario, Canada.

Country: Canada

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: J Rheumatol

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Symptomatic acute reactive arthritis after an outbreak of salmonella Related Publications

• Abrupt Slowing of the Cerebral Circulation.
• Analysis of single nucleotide polymorphisms in Toll-like receptor 4 shows no association with ankylosing spondylitis in a Korean population.
• Assessment of the impact of flares in ankylosing spondylitis disease activity using the Flare Illustration.
• Body weight and weight loss: are health messages reaching their target?
• Cell-mediated lympholysis of N-(3-nitro-4-hydroxy-5-iodophenylacetyl)-beta-anaylglycylglycyl-modified autologous lymphocytes. Effector cell specificity to modified cell surface components controlled by the H-2K and H-2D serological regions of the murine m
• Cerebral MR imaging in intravascular lymphomatosis.
• Clinical observations on morbid periodicity.
• DISCUSSION OF THE PATHOLOGICAL DIVISION OF ST. LUKE'S HOSPITAL CLINICAL CLUB.
• Editorial comment.
• Emotional factors in eye disease.
• Environmental Allergens: With Special Reference to Their Importance and Specificity.
• Ewing's tumor.
• Fatal agranulocytosis attributed to co-trimoxazole therapy.
• MILD MENTAL DISTURBANCES-PREVALENT CAUSES.
• NEUROLOGICAL FINDINGS IN ONE THOUSAND GROUP STUDY CASES.
• NOTES ON PATHOLOGICAL REFLEXES.
• NOTES ON SYPHILIS OF THE CENTRAL NERVOUS SYSTEM.
• Nerve Injuries: Their Influence on the Period of Disability.
• Oral contraceptives and death from myocardial infarction.
• Oral contraceptives and fatal subarachnoid haemorrhage.
• Retinol (vitamin A) and retinol-binding protein levels are decreased in ankylosing spondylitis: clinical and genetic analysis.
• Routine Examination of the Cerebrospinal Fluid in Suspected Syphilis of the Nervous System.
• SOME COMPARISONS BETWEEN WAR NEUROSES AND THOSE OF CIVIL LIFE.
• Study of fatal bone marrow depression with special reference to phenylbutazone and oxyphenbutazone.
• Symptomatic acute reactive arthritis after an outbreak of salmonella.
• THE NEUROLOGICAL ASPECTS AND LATE SYMPTOMS OF EPIDEMIC ENCEPHALITIS.
• THE NEUROLOGICAL ASPECTS OF VISCEROPTOSIS.
• Teratogenesis and lymphocyte stimulation.
• The Canadian Rheumatology Association/ Spondyloarthritis Research Consortium of Canada treatment recommendations for the management of spondyloarthritis: a national multidisciplinary stakeholder project.
• Volume of liquor amnii in normal and abnormal pregnancy.