Symptom patterns in unipolar and bipolar depression correlating with monoamine metabolites in the cerebrospinal fluid: II. Suicide.

Symptom patterns in unipolar and bipolar depression correlating with monoamine metabolites in the cerebrospinal fluid: II. Suicide. Research Abstract Details 

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Symptom patterns in unipolar and bipolar depression correlating with monoamine metabolites in the cerebrospinal fluid: II. Suicide. Abstract Text:

Suicidality scores from the Schedule for Affective Disorders and Schizophrenia on 21 unipolar and 12 bipolar depressives were correlated with monoamine metabolites in the cerebrospinal fluid using multiple regression analyses. The single item of Suicidal Tendencies Worst Week correlated highly significantly and negatively with 3-methoxy-4-hydroxyphenylglycol (MHPG) and only to a very slight degree with 5-hydroxyindoleacetic acid (5HIAA). Seriousness of Intent of Worst Suicide Attempt earlier in life correlated significantly and negatively with both MHPG and 5HIAA. Subjective Anger was positively and Overt Anger negatively associated with thoughts of suicide. The results support earlier reports that depressives with low 5HIAA are prone to violent suicides, but also point to the equal, if not even greater involvement of MHPG and noradrenergic neuronal systems in carrying out a wish for death.

Symptom patterns in unipolar and bipolar depression correlating with monoamine metabolites in the cerebrospinal fluid: II. Suicide. Publishing Authors By Initials

For similar behavior and behavior mechanisms: behavior: behavioral symptoms: self-injurious behavior: suicide research abstracts see: behavior and behavior mechanisms: behavior: behavioral symptoms: self-injurious behavior: suicide research

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Symptom patterns in unipolar and bipolar depression correlating with monoamine metabolites in the cerebrospinal fluid: II. Suicide. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Psychiatry research

VOLUME: 3

Page Numbers: 225-36

Journal Abbreviation: Psychiatry Res

ISSN: 0165-1781

DAY: 17

MONTH: Oct

YEAR: 1980

Symptom patterns in unipolar and bipolar depression correlating with monoamine metabolites in the cerebrospinal fluid: II. Suicide. Information

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LANGUAGE: eng

NlmUniqueID: 7911385

Symptom patterns in unipolar and bipolar depression correlating with monoamine metabolites in the cerebrospinal fluid: II. Suicide. Keywords Mesh Terms:

KEYWORDS: Suicide

MESH TERMS: cerebrospinal fluid

Chemical & Substance for Abstract: Symptom patterns in unipolar and bipolar depression correlating with monoamine metabolites in the cerebrospinal fluid: II. Suicide. Information

Substance Name: Hydroxyindoleacetic Acid

Registry Number: 54-16-0

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Country: NETHERLANDS

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MEDLINETA: Psychiatry Res

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