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Switch-peptides: controlling self-assembly of amyloid beta-derived peptides in vitro by consecutive triggering of acyl migrations.

Switch-peptides: controlling self-assembly of amyloid beta-derived peptides in vitro by consecutive triggering of acyl migrations. Research Abstract Details 

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  • Switch-peptides: controlling self-assembly of amyloid beta-derived peptides in vitro by consecutive triggering of acyl migrations. Abstract Text:

    sonia dos santosSonia Dos Santos,arunan chandravarkarArunan Chandravarkar,bhubaneswar mandalBhubaneswar Mandal,richard mimnaRichard Mimna,karine muratKarine Murat,lydiane Lydiane ,patricia tellaPatricia Tella,gabriele tuchschererGabriele Tuchscherer,manfred mutterManfred Mutter,

    The sequential triggering (Soff --> Son) of O, N-acyl migrations (AcM) by chemical and enzymatic methods (Ti) in peptides containing structure-disrupting switch-elements, S (switch-peptides), offers a novel tool for studying in statu nascendi the onset and inhibition of polypeptide folding and self-assembly as a key process in degenerative diseases.

    Switch-peptides: controlling self-assembly of amyloid beta-derived peptides in vitro by consecutive triggering of acyl migrations. Publishing Authors By Initials

    s dos santosS Dos Santos,a chandravarkarA Chandravarkar,b mandalB Mandal,r mimnaR Mimna,k muratK Murat,l L ,p tellaP Tella,g tuchschererG Tuchscherer,m mutterM Mutter,

    For similar biochemical phenomena, metabolism, and nutrition: biochemical phenomena: molecular structure: molecular conformation: protein conformation research abstracts see: biochemical phenomena, metabolism, and nutrition: biochemical phenomena: molecular structure: molecular conformation: protein conformation research

    PUBMED ID PMID:

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    Switch-peptides: controlling self-assembly of amyloid beta-derived peptides in vitro by consecutive triggering of acyl migrations. Journal Published:

    PUBLICATION TYPE: Research Support, Non-U.S. Gov

    Journal: Journal of the American Chemical Society

    VOLUME: 127

    Page Numbers: 11888-9

    Journal Abbreviation: J. Am. Chem. Soc.

    ISSN: 0002-7863

    DAY: 31

    MONTH: Aug

    YEAR: 2005

    Switch-peptides: controlling self-assembly of amyloid beta-derived peptides in vitro by consecutive triggering of acyl migrations. Information

    Number of References:

    LANGUAGE: eng

    NlmUniqueID: 7503056

    Switch-peptides: controlling self-assembly of amyloid beta-derived peptides in vitro by consecutive triggering of acyl migrations. Keywords Mesh Terms:

    KEYWORDS: Protein Conformation

    MESH TERMS: metabolism

    Chemical & Substance for Abstract: Switch-peptides: controlling self-assembly of amyloid beta-derived peptides in vitro by consecutive triggering of acyl migrations. Information

    Substance Name: Peptides

    Registry Number: 0

    Grant and Affiliation Information for Switch-peptides: controlling self-assembly of amyloid beta-derived peptides in vitro by consecutive triggering of acyl migrations.

    AFFILIATION: Ecole Polytechnique Fédérale de Lausanne (EPFL), Institute of Chemical Sciences and Engineering, CH-1015 Lausanne, Switzerland.

    Country: United States

    United States Research PublicationUnited States Research Publication

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    MEDLINETA: J Am Chem Soc

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