[Susceptibility to endometriosis in women of Han Nationality in Guangdong Province associated with Msp I polymorphisms of cytochrome P450 1A1 gene]

[Susceptibility to endometriosis in women of Han Nationality in Guangdong Province associated with Msp I polymorphisms of cytochrome P450 1A1 gene] Research Abstract Details 

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[Susceptibility to endometriosis in women of Han Nationality in Guangdong Province associated with Msp I polymorphisms of cytochrome P450 1A1 gene] Abstract Text:

Dong-xian Peng,Yuan-li He,Li-wen Qiu,Fang Yang,Jing-ming Lin,

OBJECTIVE: To assess the possible association of the Msp I polymorphisms of cytochrome P4501A1(CYP1A1) gene with the susceptibility to endometriosis in women of Han Nationality in Guangdong Province. METHODS: Polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) was employed to analyze the 3 genotypes m1m1, m1m2 and m2m2 in 3'-flanking region of CYP1A1 in 76 patients with endometriosis and 80 healthy controls. RESULTS: The frequencies of genotypes m1m1, m1m2 and m2m2 were 30.3 %, 50.0 % and 19.7 % in patients with endometriosis while 42.5 %, 45.0 % and 12.5 % in the controls, respectively, showing no statistically significant difference in the frequencies of the three genotypes between the 2 groups. The frequencies of two alleles were of no significant difference between the patients and controls, either. CONCLUSION: Msp I polymorphisms of cytochrome P4501A1 in itself might not be associated with the susceptibility to endometriosis in women of Han Nationality in Guangdong Province.

[Susceptibility to endometriosis in women of Han Nationality in Guangdong Province associated with Msp I polymorphisms of cytochrome P450 1A1 gene] Publishing Authors By Initials

DX Peng,YL He,LW Qiu,F Yang,JM Lin,

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[Susceptibility to endometriosis in women of Han Nationality in Guangdong Province associated with Msp I polymorphisms of cytochrome P450 1A1 gene] Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Di 1 jun yi da xue xue bao = Academic journal of t

VOLUME: 22

Page Numbers: 814-6

Journal Abbreviation: Di Yi Jun Yi Da Xue Xue Bao

ISSN: 1000-2588

DAY: 25

MONTH: Sep

YEAR: 2002

[Susceptibility to endometriosis in women of Han Nationality in Guangdong Province associated with Msp I polymorphisms of cytochrome P450 1A1 gene] Information

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LANGUAGE: chi

NlmUniqueID: 9426110

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AFFILIATION: Department of Obstetrics and Gynecology, Zhujiang Hospital, First Military Medical University, Guangzhou 510282, China. pdx@fimmu.com

Country: China

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MEDLINETA: Di Yi Jun Yi Da Xue Xue Bao

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