SUMO and NF-kappaB ties.

SUMO and NF-kappaB ties. Research Abstract Details 

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SUMO and NF-kappaB ties. Abstract Text:

A M Mabb,S Miyamoto,

Members of the NF-kappaB family of transcription factors play critical roles in regulating immunity and cell survival and contribute to cancer progression and chemoresistance. Over the past 20 years, much has been learned about the remarkable complexity in regulation of NF-kappaB signaling. In particular, recent studies have added to our current understanding of the roles of a multitude of posttranslational modifications in this signaling system: these include phosphorylation, acetylation, nitrosylation, ubiquitination, neddylation and sumoylation. This review will highlight our current knowledge of the roles of sumoylation in regulating NF-kappaB signaling and functions and will address future perspectives.

SUMO and NF-kappaB ties. Publishing Authors By Initials

AM Mabb,S Miyamoto,

For similar genetic processes: gene expression: transcription, genetic research abstracts see: genetic processes: gene expression: transcription, genetic research

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SUMO and NF-kappaB ties. Journal Published:

PUBLICATION TYPE: Review

Journal: Cellular and molecular life sciences : CMLS

VOLUME: 64

Page Numbers: 1979-96

Journal Abbreviation: Cell. Mol. Life Sci.

ISSN: 1420-682X

DAY: 3

MONTH: Aug

YEAR: 2007

SUMO and NF-kappaB ties. Information

Number of References: 125

LANGUAGE: eng

NlmUniqueID: 9705402

SUMO and NF-kappaB ties. Keywords Mesh Terms:

KEYWORDS: Transcription, Genetic

MESH TERMS: physiology

Chemical & Substance for Abstract: SUMO and NF-kappaB ties. Information

Substance Name: I-kappa B Kinase

Registry Number: EC 2.7.1.37

Grant and Affiliation Information for SUMO and NF-kappaB ties.

AFFILIATION: Program in Molecular and Cellular Pharmacology, Department of Pharmacology, University of Wisconsin, 301 Medical Sciences Center, 1300 University Avenue, Madison, WI 53706, USA.

Country: Switzerland

AGENCY: United States NCI

GRANT: R01CA077474

ACRONYM: CA

MEDLINETA: Cell Mol Life Sci

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