Sulphatoxy melatonin: an index of depression in anorexia nervosa and bulimia nervosa.

Sulphatoxy melatonin: an index of depression in anorexia nervosa and bulimia nervosa. Research Abstract Details 

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Sulphatoxy melatonin: an index of depression in anorexia nervosa and bulimia nervosa. Abstract Text:

Urinary excretion of the principal melatonin metabolite, sulphatoxy melatonin (aMT6s), was assessed both during the day and during the night in 38 female eating disorder patients (anorexia nervosa, n = 17; bulimia nervosa, n = 12; anorexia nervosa + bulimia nervosa, n = 9) and 14 female control subjects. Correlations between nocturnal serum melatonin and urinary aMT6s were also obtained. All patient groups and the controls showed a preservation of diurnal rhythm with elevated nocturnal urinary aMT6s values and no significant difference in amplitude between groups. However, patients with concurrent major depression had significantly lower levels of daytime and nighttime urinary aMT6s than the nondepressed group. Weight did not influence these findings. Correlations between nocturnal serum melatonin levels and urinary aMT6s were high for control subjects (r = 0.77) and moderate for the patient groups (r = 0.31). This may reflect differences in the rate of excretion of melatonin between patients and controls.

Sulphatoxy melatonin: an index of depression in anorexia nervosa and bulimia nervosa. Publishing Authors By Initials

For similar behavioral disciplines and activities: psychiatric status rating scales research abstracts see: behavioral disciplines and activities: psychiatric status rating scales research

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Sulphatoxy melatonin: an index of depression in anorexia nervosa and bulimia nervosa. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Psychiatry research

VOLUME: 32

Page Numbers: 221-7

Journal Abbreviation: Psychiatry Res

ISSN: 0165-1781

DAY: 17

MONTH: Jun

YEAR: 1990

Sulphatoxy melatonin: an index of depression in anorexia nervosa and bulimia nervosa. Information

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LANGUAGE: eng

NlmUniqueID: 7911385

Sulphatoxy melatonin: an index of depression in anorexia nervosa and bulimia nervosa. Keywords Mesh Terms:

KEYWORDS: Psychiatric Status Rating Scales

MESH TERMS: urine

Chemical & Substance for Abstract: Sulphatoxy melatonin: an index of depression in anorexia nervosa and bulimia nervosa. Information

Substance Name: Melatonin

Registry Number: 73-31-4

Grant and Affiliation Information for Sulphatoxy melatonin: an index of depression in anorexia nervosa and bulimia nervosa.

AFFILIATION: Department of Psychiatry, University of Toronto, Ont., Canada.

Country: IRELAND

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MEDLINETA: Psychiatry Res

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