Substrate control of termination of fatty acid biosynthesis by fatty acid synthetase from Brevibacterium ammoniagenes.

Substrate control of termination of fatty acid biosynthesis by fatty acid synthetase from Brevibacterium ammoniagenes. Research Abstract Details 

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Substrate control of termination of fatty acid biosynthesis by fatty acid synthetase from Brevibacterium ammoniagenes. Abstract Text:

A Kawaguchi,K Arai,Y Seyama,T Yamakawa,S Okuda,

The pattern of fatty acids produced by the fatty acid synthetase complex of Brevibacterium ammoniagenes under several conditions was examined. The fatty acid synthetase obtained from B. ammoniagenes produced oleic acid as well as saturated fatty acids (palmitic and stearic acids). The relative proportions of palmitic to stearic acids varied over a wide range. Such alterations were dependent on the malonyl-CoA concentration and the ratio of acetyl-CoA to malonyl-CoA concentrations. At malonyl-CoA concentrations higher than 100 microM, stearic acid accounted for more than 90% of the saturated fatty acids and the pattern of fatty acid synthesized was independent on the ratio of acetyl-CoA to malonyl-CoA. At malonyl-CoA concentrations lower than 100 microM, raising the acetyl-CoA/malonyl-CoA ratio increased the percentage of palmitic acid. However, the proportion of oleic acid produced remained almost constant under all conditions tested.

Substrate control of termination of fatty acid biosynthesis by fatty acid synthetase from Brevibacterium ammoniagenes. Publishing Authors By Initials

A Kawaguchi,K Arai,Y Seyama,T Yamakawa,S Okuda,

For similar lipids: fatty acids: fatty acids, unsaturated: fatty acids, monounsaturated: oleic acids research abstracts see: lipids: fatty acids: fatty acids, unsaturated: fatty acids, monounsaturated: oleic acids research

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Substrate control of termination of fatty acid biosynthesis by fatty acid synthetase from Brevibacterium ammoniagenes. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Journal of biochemistry

VOLUME: 88

Page Numbers: 303-6

Journal Abbreviation: J. Biochem.

ISSN: 0021-924X

DAY: 19

MONTH: Aug

YEAR: 1980

Substrate control of termination of fatty acid biosynthesis by fatty acid synthetase from Brevibacterium ammoniagenes. Information

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LANGUAGE: eng

NlmUniqueID: 376600

Substrate control of termination of fatty acid biosynthesis by fatty acid synthetase from Brevibacterium ammoniagenes. Keywords Mesh Terms:

KEYWORDS: Oleic Acids

MESH TERMS: pharmacology

Chemical & Substance for Abstract: Substrate control of termination of fatty acid biosynthesis by fatty acid synthetase from Brevibacterium ammoniagenes. Information

Substance Name: Fatty Acid Synthetase Complex

Registry Number: EC 6.-

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Country: JAPAN

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MEDLINETA: J Biochem

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