[Study on the distribution of vitamin D receptor gene start codon polymorphism in the Achangs and Hans]

[Study on the distribution of vitamin D receptor gene start codon polymorphism in the Achangs and Hans] Research Abstract Details 

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[Study on the distribution of vitamin D receptor gene start codon polymorphism in the Achangs and Hans] Abstract Text:

Ji-mei Li,Hua-jun Lu,Hai-lin Li,Rui-zhu Tang,Xiao-xian Wang,Ping Hao,

OBJECTIVE: To detect the difference between the Chinese Achang and Han ethnic groups in Yunnan province in the distribution of vitamin D receptor (VDR) gene start codon polymorphism. METHODS: Polymerase chain reaction-restriction fragment length polymorphism, gene sequencing and genetic analysis methods were used. A restriction fragment length polymorphism in the start codon of VDR (Fok I) gene was tested in the Achangs (n=68) and the Hans (n=92). RESULTS: The frequencies of FF, Ff and ff genotypes were found to be 18%, 35% and 47% in the Achangs, and 22%, 52% and 26% in the Hans, respectively. A significant difference was seen in the frequency distribution of VDR genotype between the Achangs and the Hans(Chi2=7.716, P=0.021). CONCLUSION: The Achang and Han ethnic groups differ in the frequency distribution of VDR gene start codon polymorphism.

[Study on the distribution of vitamin D receptor gene start codon polymorphism in the Achangs and Hans] Publishing Authors By Initials

JM Li,HJ Lu,HL Li,RZ Tang,XX Wang,P Hao,

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[Study on the distribution of vitamin D receptor gene start codon polymorphism in the Achangs and Hans] Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Zhonghua yi xue yi chuan xue za zhi = Zhonghua yix

VOLUME: 20

Page Numbers: 315-7

Journal Abbreviation: Zhonghua Yi Xue Yi Chuan Xue Z

ISSN: 1003-9406

DAY: 6

MONTH: Aug

YEAR: 2003

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LANGUAGE: chi

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AFFILIATION: Clinical Research Center, the First Affiliated Hospital, Kunming Medical College, Kunming, Yunnan, 650032 PR China.

Country: China

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MEDLINETA: Zhonghua Yi Xue Yi Chuan Xue Z

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