[Study on the correlation of the biochemical indexes in flouride workers]

[Study on the correlation of the biochemical indexes in flouride workers] Research Abstract Details 

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[Study on the correlation of the biochemical indexes in flouride workers] Abstract Text:

Zhijun Huang,Kejun Li,Gang Hou,Zhenhe Shen,Cui Wang,Kaiyou Jiang,Xiaofang Luo,

OBJECTIVE: To explore the correlation among some biochemical indexes in the fluoride workers. METHODS: The activities of superoxide dismutase(SOD), glutathione peroxidase (GSH-Px), catalase (CAT), alkaline phosphatase (AKP) and the level of calcitonin (CT), parathyroid hormone (PTH), IgG, IgA, IgM, Cu2+, Zn2+, Ca2+, Mg2+ and Se2+, F- in serum and in urine were measured in fifty male fluoride workers and fifty controls. RESULTS: The levels of F-, CT, PTH, AKP and GSH-Px in serum and F- in urine in exposed group were significantly different from that in control group. Correlation analysis indicated that F- in urine and CAT(r = 0.3133, P < 0.05), CT and PTH(r = 0.5173, P < 0.01), Se2+ and CAT(r = 0.4354, P < 0.05) were positively correlated. There were significantly negative correlation between F- in serum and GSH-Px (r = -0.5202, P < 0.01) and positive correlation among Cu2+, Zn2+, Ca2+ and Mg2+ in serum. CONCLUSION: (1) Excess of fluoride may affect secretion of calcium adjusting hormone (CT, PTH); (2) Changes of AKP and GSH-Px may be regarded as health monitoring indexes; (3) The correlation of biochemical indexes plays an important role in studying the mechanism and the early prevention and treatment of industrial fluorosis.

[Study on the correlation of the biochemical indexes in flouride workers] Publishing Authors By Initials

Z Huang,K Li,G Hou,Z Shen,C Wang,K Jiang,X Luo,

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[Study on the correlation of the biochemical indexes in flouride workers] Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Zhonghua lao dong wei sheng zhi ye bing za zhi = Z

VOLUME: 20

Page Numbers: 192-4

Journal Abbreviation: Zhonghua Lao Dong Wei Sheng Zh

ISSN: 1001-9391

DAY: 25

MONTH: Jun

YEAR: 2002

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LANGUAGE: chi

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Grant and Affiliation Information for [Study on the correlation of the biochemical indexes in flouride workers]

AFFILIATION: Henan Institute of Occupational Disease, Zhengzhou 450052, China.

Country: China

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MEDLINETA: Zhonghua Lao Dong Wei Sheng Zh

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