[Study on the anti-maturation features of immature dendritic cells induced by low dose of granulocyte macrophage colony stimulating factor]

[Study on the anti-maturation features of immature dendritic cells induced by low dose of granulocyte macrophage colony stimulating factor] Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

[Study on the anti-maturation features of immature dendritic cells induced by low dose of granulocyte macrophage colony stimulating factor] Abstract Text:

Qiang Wang,Yi-zhi Peng,

OBJECTIVE: To investigate the influence of maturative agents, including lipopolysaccharide (LPS), tumor necrosis factor alpha (TNF-alpha) and interferon gamma(IFN-gamma) on the maturation of immature dendritic cells originated from murine bone marrow induced by low dose of granulocyte macrophage colony stimulating factor (rm GM-CSF). METHODS: Dendritic cells from murine bone marrow progenitors were cultured in low and high doses of GM-CSF for 6 days, and then the suspending cells were harvested for the experiment. After 3 days of co-culture of the obtained DC with low dose rmGM-CSF (GM(low)DC) with LPS, TNF-alpha and IFN-gamma, the stimulatory capacity of inducing proliferation of non-sensitized splenocytes of GM(low)DC in mixed lymphocyte reaction (MLR) was observed and compared with that of GM(high)DC. RESULTS: GM(low)DC could not activate the non-sensitized splenocytes or induce it into proliferation after 3 days of co-incubation with LPS, TNF-alpha, IFN-gamma, with the stimulation index (SI) lower than 2. Whereas GM(high)DC could strongly activate naive splenocytes (SI = 4.71). CONCLUSION: GM(low)DC was resistant to maturation and insensitive to the stimulation by LPS, TNF-alpha or IFN-gamma.

[Study on the anti-maturation features of immature dendritic cells induced by low dose of granulocyte macrophage colony stimulating factor] Publishing Authors By Initials

Q Wang,YZ Peng,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

[Study on the anti-maturation features of immature dendritic cells induced by low dose of granulocyte macrophage colony stimulating factor] Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Zhonghua shao shang za zhi = Zhonghua shaoshang za

VOLUME: 20

Page Numbers: 327-9

Journal Abbreviation:

ISSN: 1009-2587

DAY: 25

MONTH: Dec

YEAR: 2004

[Study on the anti-maturation features of immature dendritic cells induced by low dose of granulocyte macrophage colony stimulating factor] Information

Number of References:

LANGUAGE: chi

NlmUniqueID: 100959418

[Study on the anti-maturation features of immature dendritic cells induced by low dose of granulocyte macrophage colony stimulating factor] Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: [Study on the anti-maturation features of immature dendritic cells induced by low dose of granulocyte macrophage colony stimulating factor] Information

Substance Name:

Registry Number:

Grant and Affiliation Information for [Study on the anti-maturation features of immature dendritic cells induced by low dose of granulocyte macrophage colony stimulating factor]

AFFILIATION: Institute of Burn Research, Southwest Hospital, State Key Laboratory of Trauma, Burns and Combined Injury, The Third Military Medical University, Chongqing, 400038, P.R. China.

Country: China

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Zhonghua Shao Shang Za Zhi

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Study on the anti-maturation features of immature dendritic cells induced by low dose of granulocyte macrophage colony stimulating factor Related Publications

• Complications in children with long-term cochlear implants.
• Glycerate-oxidizing activity of glycolate oxidase from leaves of Spinacia oleracea.
• Highly luminescent, stable, and water-soluble CdSe/CdS core-shell dendron nanocrystals with carboxylate anchoring groups.
• Treatment of Meniere's disease with a heavy dosage of gu sui bu (Rhizoma Drynariae).
• [A two-dimensional electrophoresis protocol suitable for proteomic study of rice leaves]
• [Comparative studies on the difference between Ascaris lumbricoides and Ascaris suum]
• [Detection of the optimum resolution of monochromator]
• [Determination of Cu, Pb, Sn, Fe and Zn in the ancient Chinese bronzes by X-ray fluorescence filter paper method]
• [Determination of rhodojaponin, a novel botanical insecticide by HPTLC]
• [Determination of trace rare earth impurities in the high-purity lanthanum oxide by chemical spectrographic analysis]
• [Diagnosis and treatment of gluteal muscle contracture associated with unequal leg length caused by pelvis obliquity]
• [Effect of Sim2 gene on the differentiation of PC12 cells]
• [Effect of soy isoflavone on gene expression of leptin and insulin sensibility in insulin-resistant rats]
• [Fabrication of a blood vessel scaffold with a combined polymer for tissue engineering]
• [Improving the management of deep partial thickness burn wound]
• [Influence of angiotensin-converting enzyme gene polymorphism on the anti-proteinuria efficacy of angiotensin-converting enzyme inhibitor in Han nationality of southern Sichuan province in China]
• [Influence of cryoprotectant and cooling rate in vitrification method on the spindles of rabbit oocytes.]
• [Investigation on hepatitis G virus (HGV) infection among different populations in Shenzhen]
• [Long-term expansion of T cell progenitors by JAK3 gene transduced primitive hematopoietic cells in vitro]
• [Retroviral-mediated transfection of hepatitis B virus core gene into bone marrow-derived dendritic cells]
• [Spectroscopic studies on transition metal ions in colored diamonds]
• [Study of the clinical factors associated with glomerular filtration rate]
• [Study on the anti-maturation features of immature dendritic cells induced by low dose of granulocyte macrophage colony stimulating factor]
• [Successful emergency treatment of a case with severe hemolytic disease of the newborn due to maternal Rh deletion phenotype-D]
• [Targeting of nitric oxide-donor and related drugs]
• [The hardware design of a portable gastrointestinal wireless endoscope image receiver]
• [The influence of continuous renal replacement therapy on the plasma levels of endotoxin and cytokines in severely burned patients with sepsis]
• [The influence of temperature on the protein expression of human lung cancer cell line A549]
• [The oxidation degradation of great green SF by Fenton reagent]
• [The research advance of analytical methodology for detecting bovine spongiform encephalopathy]