Studies with a duck embryo adapted goose parvovirus vaccine.

Studies with a duck embryo adapted goose parvovirus vaccine. Research Abstract Details 

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Studies with a duck embryo adapted goose parvovirus vaccine. Abstract Text:

A goose parvovirus isolated from goslings with Derzsy's disease was adapted to growth in embryonating duck eggs. After 22 passages the adapted parvovirus was evaluated in 1 to 3-day-old susceptible goslings for attenuation and immunogenicity. The response to vaccination was measured by virus neutralisation (VN) tests and resistance to experimental challenge. The results showed that the duck embryo adapted parvovirus vaccine was apathogenic for goslings and stimulated significant VN antibody levels for up to 20 weeks. Virus was reisolated from the faeces of vaccinated goslings for up to 3 weeks after vaccination. In contact control goslings remained serologically negative until 6 weeks after contact when low levels of antibody were detected. Goslings vaccinated subcutaneously were resistant to experimental challenge 2 days after vaccination. Vaccination of goslings by subcutaneous and foot web routes produced complete protection to challenge. Goslings given vaccine via their drinking water were not resistant to challenge. The results suggest that the duck embryo adapted goose parvovirus vaccine induces a good immune response in susceptible goslings. However, further work is necessary to investigate whether the vaccine retains its attenuation following gosling to gosling passage.

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Studies with a duck embryo adapted goose parvovirus vaccine. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Avian pathology : journal of the W.V.P.A

VOLUME: 11

Page Numbers: 503-10

Journal Abbreviation: Avian Pathol.

ISSN: 0307-9457

DAY: 4

MONTH: 09

YEAR: 1982

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LANGUAGE: eng

NlmUniqueID: 8210638

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Grant and Affiliation Information for Studies with a duck embryo adapted goose parvovirus vaccine.

AFFILIATION: Poultry Department, Central Veterinary Laboratory, New Haw, Weybridge, Surrey, England.

Country: England

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MEDLINETA: Avian Pathol

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