Structural basis for the coevolution of a viral RNA-protein complex.

Structural basis for the coevolution of a viral RNA-protein complex. Research Abstract Details 

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Structural basis for the coevolution of a viral RNA-protein complex. Abstract Text:

Jeffrey A Chao,Yury Patskovsky,Steven C Almo,Robert H Singer,

The cocrystal structure of the PP7 bacteriophage coat protein in complex with its translational operator identifies a distinct mode of sequence-specific RNA recognition when compared to the well-characterized MS2 coat protein-RNA complex. The structure reveals the molecular basis of the PP7 coat protein's ability to selectively bind its cognate RNA, and it demonstrates that the conserved beta-sheet surface is a flexible architecture that can evolve to recognize diverse RNA hairpins.

Structural basis for the coevolution of a viral RNA-protein complex. Publishing Authors By Initials

JA Chao,Y Patskovsky,SC Almo,RH Singer,

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Structural basis for the coevolution of a viral RNA-protein complex. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Nature structural & molecular biology

VOLUME: 15

Page Numbers: 103-5

Journal Abbreviation: Nat. Struct. Mol. Biol.

ISSN: 1545-9985

DAY: 9

MONTH: 12

YEAR: 2007

Structural basis for the coevolution of a viral RNA-protein complex. Information

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LANGUAGE: eng

NlmUniqueID: 101186374

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Grant and Affiliation Information for Structural basis for the coevolution of a viral RNA-protein complex.

AFFILIATION: Department of Anatomy, Albert Einstein College of Medicine, 1300 Morris Park Ave, Bronx, New York 10461, USA.

Country: United States

AGENCY: United States NIBIB

GRANT: EB-002060

ACRONYM: EB

MEDLINETA: Nat Struct Mol Biol

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ACCESSION NUMBER: 2QUX

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