Stimulation of protein synthesis and breakdown by vaccination.

Stimulation of protein synthesis and breakdown by vaccination. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Stimulation of protein synthesis and breakdown by vaccination. Abstract Text:

Six normal volunteers were vaccinated against typhoid-cholera. 15N-Glycine was injected the morning after vaccination. The injection was repeated three to six days and 10 days later. All subjects ate the same diet on each occasion. Excretion of 15N in urinary ammonia and total urinary excretion of nitrogen, ammonia, and creatinine were determined after each injection of isotope. Urinary excretion of 15N was used to calculate rates of whole-body protein turnover. Total urinary nitrogen and ammonia excretions showed no appreciable change on all three days. Creatinine excretion was significantly higher the day after vaccination than on the other two days (p < 0.05). Rates of protein turnover were also significantly higher on this day: a 37% increase in synthesis and 55% increase in degradation were noted. These results show that during the reaction to vaccination there was a stimulation of whole-body protein metabolism that is similar to that produced by sepsis.

Stimulation of protein synthesis and breakdown by vaccination. Publishing Authors By Initials

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

Stimulation of protein synthesis and breakdown by vaccination. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: British medical journal

VOLUME: 281

Page Numbers: 263-5

Journal Abbreviation: Br Med J

ISSN: 0007-1447

DAY: 26

MONTH: Jul

YEAR: 1980

Stimulation of protein synthesis and breakdown by vaccination. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 372673

Stimulation of protein synthesis and breakdown by vaccination. Keywords Mesh Terms:

KEYWORDS: Vaccination

MESH TERMS: metabolism

Chemical & Substance for Abstract: Stimulation of protein synthesis and breakdown by vaccination. Information

Substance Name: Nitrogen

Registry Number: 7727-37-9

Grant and Affiliation Information for Stimulation of protein synthesis and breakdown by vaccination.

AFFILIATION:

Country: ENGLAND

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Br Med J

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Stimulation of protein synthesis and breakdown by vaccination Related Publications

• Back pain.
• Classification and definition of protein-calorie malnutrition.
• Classification and definition of protein-energy malnutrition.
• Feeding the world in the new millennium.
• Fibrosis of the liver in West African children.
• Metabolic bone disease in Asians.
• Observations on enzymes in the human liver: general considerations and preliminary results.
• Protein malnutrition and albumin breakdown.
• Protein metabolism in the malnourished infant.
• Protein synthesis and breakdown after vaccination.
• Protein turnover and nutrition: the beginnings of a new development.
• Stimulation of protein synthesis and breakdown by vaccination.
• The history of the Tropical Metabolism Research Unit - U.W.I.
• The protein content of liver and muscle as a measure of protein deficiency in human subjects.
• The treatment and prognosis of infantile malnutrition in Jamaican children.
• Theoretical analysis of the importance of recycling in measurements of protein turnover by constant infusion of a labelled amino acid.
• Total exchangeable potassium in infantile malnutrition.
• Undernutrition should be the first priority.