Stimulation of net muscle protein synthesis by whey protein ingestion before and after exercise.

Stimulation of net muscle protein synthesis by whey protein ingestion before and after exercise. Research Abstract Details 

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Stimulation of net muscle protein synthesis by whey protein ingestion before and after exercise. Abstract Text:

Kevin D Tipton,Tabatha A Elliott,Melanie G Cree,Asle A Aarsland,Arthur P Sanford,Robert R Wolfe,

Timing of nutrient ingestion has been demonstrated to influence the anabolic response of muscle following exercise. Previously, we demonstrated that net amino acid uptake was greater when free essential amino acids plus carbohydrates were ingested before resistance exercise rather than following exercise. However, it is unclear if ingestion of whole proteins before exercise would stimulate a superior response compared with following exercise. This study was designed to examine the response of muscle protein balance to ingestion of whey proteins both before and following resistance exercise. Healthy volunteers were randomly assigned to one of two groups. A solution of whey proteins was consumed either immediately before exercise (PRE; n = 8) or immediately following exercise (POST; n = 9). Each subject performed 10 sets of 8 repetitions of leg extension exercise. Phenylalanine concentrations were measured in femoral arteriovenous samples to determine balance across the leg. Arterial amino acid concentrations were elevated by approximately 50%, and net amino acid balance switched from negative to positive following ingestion of proteins at either time. Amino acid uptake was not significantly different between PRE and POST when calculated from the beginning of exercise (67 +/- 22 and 27 +/- 10 for PRE and POST, respectively) or from the ingestion of each drink (60 +/- 17 and 63 +/- 15 for PRE and POST, respectively). Thus the response of net muscle protein balance to timing of intact protein ingestion does not respond as does that of the combination of free amino acids and carbohydrate.

Stimulation of net muscle protein synthesis by whey protein ingestion before and after exercise. Publishing Authors By Initials

KD Tipton,TA Elliott,MG Cree,AA Aarsland,AP Sanford,RR Wolfe,

For similar natural sciences: time: time factors research abstracts see: natural sciences: time: time factors research

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Stimulation of net muscle protein synthesis by whey protein ingestion before and after exercise. Journal Published:

PUBLICATION TYPE: Research Support, N.I.H., Extr

Journal: American journal of physiology. Endocrinology and

VOLUME: 292

Page Numbers: E71-6

Journal Abbreviation: Am. J. Physiol. Endocrinol. Me

ISSN: 0193-1849

DAY: 8

MONTH: 08

YEAR: 2006

Stimulation of net muscle protein synthesis by whey protein ingestion before and after exercise. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 100901226

Stimulation of net muscle protein synthesis by whey protein ingestion before and after exercise. Keywords Mesh Terms:

KEYWORDS: Time Factors

MESH TERMS: metabolism

Chemical & Substance for Abstract: Stimulation of net muscle protein synthesis by whey protein ingestion before and after exercise. Information

Substance Name: Insulin

Registry Number: 11061-68-0

Grant and Affiliation Information for Stimulation of net muscle protein synthesis by whey protein ingestion before and after exercise.

AFFILIATION: The Univ. of Birmingham, School of Sport & Exercise Sciences, Edgbaston, Birmington B15 2TT, UK. K.D.Tipton@Bham.ac.uk

Country: United States

AGENCY: United States NCRR

GRANT: M01 RR-00073

ACRONYM: RR

MEDLINETA: Am J Physiol Endocrinol Metab

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