Steroid receptors and response to hormonal and cytotoxic agents in vitro in two cases of androblastoma.

Steroid receptors and response to hormonal and cytotoxic agents in vitro in two cases of androblastoma. Research Abstract Details 

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Steroid receptors and response to hormonal and cytotoxic agents in vitro in two cases of androblastoma. Abstract Text:

Cytosol steroid receptor contents of 2 tubular androblastomas were determined and that was correlated with the response to hormonal (tamoxifen and medroxyprogesterone acetate) and cytotoxic agents (chlorambucil, vincristine, cisplatin and etoposide) using a new in vitro method based on ATP measurement of cultured cells. Both androblastomas showed low receptor contents and no response to medroxyprogesterone acetate, tamoxifen or their combination was found. Furthermore, there was no response to chlorambucil or vincristine or their combination as well as to the combination of tamoxifen and vincristine in one tumor. The other tumor, however, showed good in vitro response to cisplatin and the combination of cisplatin and etoposide.

Steroid receptors and response to hormonal and cytotoxic agents in vitro in two cases of androblastoma. Publishing Authors By Initials

For similar cells: cells, cultured: tumor cells, cultured research abstracts see: cells: cells, cultured: tumor cells, cultured research

PUBMED ID PMID:

MEDLINE DATE:

Steroid receptors and response to hormonal and cytotoxic agents in vitro in two cases of androblastoma. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Annales chirurgiae et gynaecologiae. Supplementum

VOLUME: 202

Page Numbers: 80-2

Journal Abbreviation:

ISSN: 0355-9874

DAY: 26

MONTH: 02

YEAR: 1987

Steroid receptors and response to hormonal and cytotoxic agents in vitro in two cases of androblastoma. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 7702959

Steroid receptors and response to hormonal and cytotoxic agents in vitro in two cases of androblastoma. Keywords Mesh Terms:

KEYWORDS: Tumor Cells, Cultured

MESH TERMS: pharmacology

Chemical & Substance for Abstract: Steroid receptors and response to hormonal and cytotoxic agents in vitro in two cases of androblastoma. Information

Substance Name: Medroxyprogesterone 17-Acetate

Registry Number: 71-58-9

Grant and Affiliation Information for Steroid receptors and response to hormonal and cytotoxic agents in vitro in two cases of androblastoma.

AFFILIATION: Department of Obstetrics and Gynecology, University Central Hospital, Turku, Finland.

Country: FINLAND

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GRANT:

ACRONYM:

MEDLINETA: Ann Chir Gynaecol Suppl

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