Stem cell heterogeneity: actual and potential stem cell compartments in mouse spermatogenesis.

Stem cell heterogeneity: actual and potential stem cell compartments in mouse spermatogenesis. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

Stem cell heterogeneity: actual and potential stem cell compartments in mouse spermatogenesis. Abstract Text:

Shosei Yoshida,Yo-Ichi Nabeshima,Toshinori Nakagawa,Shosei Yoshida,Yo-Ichi Nabeshima,Toshinori Nakagawa,

In order to assess the behavior of the spermatogonia that contribute to the stem cell system in steady-state mouse spermatogenesis, a series of pulse-labeling experiments of a subset of "undifferentiated spermatogonial" was performed using transgenic approaches. The results suggest that, in addition to the spermatogonial population that actually acts as the stem cells (actual stem cell compartment), a second set of undifferentiated spermatogonia also exists that possesses the potential to self-renew, but does not normally do so (potential stem cell compartment). The potential stem cells turn over rather rapidly, suggesting that they act as the transit amplifying cells in the normal situation. The potential stem cells seem to change their mode from transientamplification to self-renewal upon transplantation, regeneration, or loss of actual stem cells that occurs during the long reproduction period. Such a heterogeneous composition of the stem cell system may be important for the robustness of overall spermatogenesis.

Stem cell heterogeneity: actual and potential stem cell compartments in mouse spermatogenesis. Publishing Authors By Initials

S Yoshida,Y Nabeshima,T Nakagawa,S Yoshida,Y Nabeshima,T Nakagawa,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

Stem cell heterogeneity: actual and potential stem cell compartments in mouse spermatogenesis. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Annals of the New York Academy of Sciences

VOLUME: 1120

Page Numbers: 47-58

Journal Abbreviation: Ann. N. Y. Acad. Sci.

ISSN: 0077-8923

DAY: 28

MONTH: 09

YEAR: 2007

Stem cell heterogeneity: actual and potential stem cell compartments in mouse spermatogenesis. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 7506858

Stem cell heterogeneity: actual and potential stem cell compartments in mouse spermatogenesis. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: Stem cell heterogeneity: actual and potential stem cell compartments in mouse spermatogenesis. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for Stem cell heterogeneity: actual and potential stem cell compartments in mouse spermatogenesis.

AFFILIATION: Department of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Yoshida-Konoe, Sakyo, Kyoto, Kyoto 606-8501, Japan. shosei@lmls.med.kyoto-u.ac.jp.

Country: United States

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Ann N Y Acad Sci

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

Stem cell heterogeneity: actual and potential stem cell compartments in mouse spermatogenesis Related Publications

• 11-Deoxyalisol C and Alisol D: New Protostane-Type Triterpenoids from Alisma plantago-aquatica.
• A case of angioedema associated with decreased C1 inhibitor activity.
• A neural network model of metaphor understanding with dynamic interaction based on a statistical language analysis: targeting a human-like model.
• An adult form of Alexander disease: a novel mutation in glial fibrillary acidic protein.
• Characterization of progenitor domains in the developing mouse thalamus.
• Delay of cataract development in the shumiya cataract rat by the administration of drinking water containing high concentration of magnesium ion.
• Effects of frequency characteristics of reverberation time on listener envelopment.
• Efficacy of living donor liver transplantation for patients with methylmalonic acidemia.
• Efficient generation of antigen-specific cellular immunity by vaccination with poly(gamma-glutamic acid) nanoparticles entrapping endoplasmic reticulum-targeted peptides.
• Fractal-based EEG data analysis of body parts movement imagery tasks.
• Fructose, but not dextrose, accelerates the progression of chronic kidney disease.
• Gamma-aminobutyric acid (GABA) stimulates pancreatic cancer growth through overexpressing GABAA receptor pi subunit.
• Glutathione S-transferase M1 null genotype as a risk factor for carbamazepine-induced mild hepatotoxicity.
• Impact of CYP2D6*10 on H1-antihistamine-induced hypersomnia.
• In Situ Detection of Surface SiH(n) in Synchrotron-Radiation-Induced Chemical Vapor Deposition of a-Si on an SiO(2) Substrate.
• Interfacility transport of the critically ill pediatric patient.
• New Secoiridoid Glucosides from Ligustrum japonicum.
• Nuclear translocation of ADAM-10 contributes to the pathogenesis and progression of human prostate cancer.
• Overexpression of RGPR-p117 suppresses apoptotic cell death and its related gene expression in cloned normal rat kidney proximal tubular epithelial NRK52E cells.
• Pulse radiolysis study on free radical scavenger edaravone (3-methyl-1-phenyl-2-pyrazolin-5-one).
• Rectified momentum transport for a kicked Bose-Einstein condensate.
• TERT promoter-driven adenovirus vector for cancer gene therapy via systemic injection.
• The mRNA-like noncoding RNA Gomafu constitutes a novel nuclear domain in a subset of neurons.
• Thiazide diuretics exacerbate fructose-induced metabolic syndrome.
• Uncoupling of the VEGF-endothelial nitric oxide axis in diabetic nephropathy: an explanation for the paradoxical effects of VEGF in renal disease.
• [A patient with small cerebellar infarcts at tonsil and nodulus who complained of vertigo, vomiting and chest oppression]
• [Biological characteristics of an established model of ovarian cancer in mice and its homologous cell lines]
• [Coronary artery aneurysm]
• [Myocardial infarction in young patients]
• [Position of NSAIDs in causal factors of peptic ulcer]