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Standardized concept for the treatment of gastrointestinal dysmotility in critically ill patients--current status and future options.

Standardized concept for the treatment of gastrointestinal dysmotility in critically ill patients--current status and future options. Research Abstract Details 

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  • Standardized concept for the treatment of gastrointestinal dysmotility in critically ill patients--current status and future options. Abstract Text:

    michael k herbertMichael K Herbert,peter holzerPeter Holzer,

    Inhibition of gastrointestinal motility is a major problem in critically ill patients. Motor stasis gives rise to subsequent complications including intolerance to enteral feeding, enhanced permeability of the atrophic intestinal mucosa and conditions as severe as systemic inflammatory response syndrome, sepsis and multiple organ failure. Although the diagnosis of motility disturbances in critically ill patients is difficult, the type and site of the disturbance are important to consider in the analysis of the condition and in the choice of therapeutic approach. The pharmacological treatment of impaired gastrointestinal motility is difficult to handle for the clinician, because the underlying mechanisms are complex and not fully understood and the availability of pharmacological treatment options is limited. In addition, there is a lack of controlled studies on which to build an evidence-based treatment concept for critically ill patients. Notwithstanding this situation, there has been remarkable progress in the understanding of the integrated regulation of gastrointestinal motility in health and disease. These advances, which largely relate to the organization of the enteric nervous system and its signaling mechanisms, enable the intensivist to develop a standardized concept for the use of prokinetic agents in the treatment of impaired gastrointestinal motility in critically ill patients.

    Standardized concept for the treatment of gastrointestinal dysmotility in critically ill patients--current status and future options. Publishing Authors By Initials

    mk herbertMK Herbert,p holzerP Holzer,

    For similar abstracts research abstracts see: abstracts research

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    MEDLINE DATE:

    Standardized concept for the treatment of gastrointestinal dysmotility in critically ill patients--current status and future options. Journal Published:

    PUBLICATION TYPE: Journal Article

    Journal: Clinical nutrition (Edinburgh, Scotland)

    VOLUME: 27

    Page Numbers: 25-41

    Journal Abbreviation:

    ISSN: 1532-1983

    DAY: 22

    MONTH: 10

    YEAR: 2007

    Standardized concept for the treatment of gastrointestinal dysmotility in critically ill patients--current status and future options. Information

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    LANGUAGE: eng

    NlmUniqueID: 8309603

    Standardized concept for the treatment of gastrointestinal dysmotility in critically ill patients--current status and future options. Keywords Mesh Terms:

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    Grant and Affiliation Information for Standardized concept for the treatment of gastrointestinal dysmotility in critically ill patients--current status and future options.

    AFFILIATION: Department of Anaesthesiology, University of Wuerzburg, Oberduerrbacher Str. 6, 97080 Wuerzburg, Germany. Herbert_M@klinik.uni-wuerzburg.de

    Country: England

    England Research PublicationEngland Research Publication

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    MEDLINETA: Clin Nutr

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