Stabilisation of human telomeric quadruplex DNA and inhibition of telomerase by a platinum-phenanthroline complex.

Stabilisation of human telomeric quadruplex DNA and inhibition of telomerase by a platinum-phenanthroline complex. Research Abstract Details 

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Stabilisation of human telomeric quadruplex DNA and inhibition of telomerase by a platinum-phenanthroline complex. Abstract Text:

Julie E Reed,Stephen Neidle,Ramon Vilar,Julie E Reed,Stephen Neidle,Ramon Vilar,Julie E Reed,Stephen Neidle,Ramon Vilar,

Two new mono-substituted phenanthroline ligands and their platinum(ii) square planar complexes have been prepared; one of the complexes has been shown to induce a high degree of quadruplex DNA stabilisation and to inhibit telomerase.

Stabilisation of human telomeric quadruplex DNA and inhibition of telomerase by a platinum-phenanthroline complex. Publishing Authors By Initials

JE Reed,S Neidle,R Vilar,JE Reed,S Neidle,R Vilar,JE Reed,S Neidle,R Vilar,

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Stabilisation of human telomeric quadruplex DNA and inhibition of telomerase by a platinum-phenanthroline complex. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Chemical communications (Cambridge, England)

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Page Numbers: 4366-8

Journal Abbreviation: Chem. Commun. (Camb.)

ISSN: 1359-7345

DAY: 13

MONTH: 08

YEAR: 2007

Stabilisation of human telomeric quadruplex DNA and inhibition of telomerase by a platinum-phenanthroline complex. Information

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LANGUAGE: eng

NlmUniqueID: 9610838

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AFFILIATION: Department of Chemistry, Imperial College London, London, UKSW7 2AZ. r.vilar@imperial.ac.uk.

Country: England

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MEDLINETA: Chem Commun (Camb)

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