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Sperm capacitation and fertilization in mammals.

Sperm capacitation and fertilization in mammals. Research Abstract Details 

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  • Sperm capacitation and fertilization in mammals. Abstract Text:

    Current evidence and speculations concerning the nature of sperm capacitation in mammals are reviewed and critically assessed. Capacitation, a subtle functional change which must occur at least in some mammals before fertilization can take place, occurs in sperm as a result of exposure to secretions of the female tract. In some species the noncapacitated state may enable sperm to undergo a period of storage in the cauda epididymidis after completion of maturation in the mate; alternatively, the noncapacitated state may enable sperm to withstand exposure to the female tract for some time before the arrival of the egg. In several species evidence indicates capacitation enables sperm to penetrate the cumulus oophorus and the zona pellucida. Capacitation may involve changes on the sperm surface, such as the unmasking of so-called receptor sites. Both the uterus and the fallopian tube play a part in capacitation. Contraception via capacitation control by steroid therapy alone is unlikely to be achieved. The question of the need for capacitation in man is as of yet resolved. Areas reviewed include need for capacitation in different mammals, analysis of factors important for capacitation, changes in sperm during capacitation, and events involved in fertilization. Species for which definite evidence of capacitation has been found include the rat, rabbit, hamster, ferret, and sheep.

    Sperm capacitation and fertilization in mammals. Publishing Authors By Initials

    For similar urogenital system research abstracts see: urogenital system research

    PUBMED ID PMID:

    MEDLINE DATE:

    Sperm capacitation and fertilization in mammals. Journal Published:

    PUBLICATION TYPE: Journal Article

    Journal: Biology of reproduction. Supplement

    VOLUME: 2

    Page Numbers: 128-58

    Journal Abbreviation:

    ISSN:

    DAY: 7

    MONTH: 03

    YEAR: 1970

    Sperm capacitation and fertilization in mammals. Information

    Number of References:

    LANGUAGE: eng

    NlmUniqueID: 217646

    Sperm capacitation and fertilization in mammals. Keywords Mesh Terms:

    KEYWORDS: Urogenital System

    MESH TERMS:

    Chemical & Substance for Abstract: Sperm capacitation and fertilization in mammals. Information

    Substance Name: Progesterone

    Registry Number: 57-83-0

    Grant and Affiliation Information for Sperm capacitation and fertilization in mammals.

    AFFILIATION:

    Country: United States

    United States Research PublicationUnited States Research Publication

    AGENCY:

    GRANT:

    ACRONYM:

    MEDLINETA: Biol Reprod Suppl

    REFSOURCE:

    DATABASENAME:

    ACCESSION NUMBER:

    Number Hits: 0

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