To elucidate potential biological roles of human beta-synuclein, we studied its conformational changes under various conditions. The structural and functional properties of beta-synuclein were characterized using biochemical and bio-physical methods including: a functional assay, mass spectrometry, size exclusion chromatography, circular dichroism (CD), and fluorescence spectroscopy. The results showed beta-synuclein has a high proportion of random coil in solution.
Spectroscopic and Functional Characterization of Human beta-Synuclein. Publishing Authors By Initials
Spectroscopic and Functional Characterization of Human beta-Synuclein. Journal Published:
PUBLICATION TYPE: Journal Article
Journal: Protein and peptide letters
VOLUME: 14
Page Numbers: 1021-6
Journal Abbreviation: Protein Pept. Lett.
ISSN: 0929-8665
DAY: 28
MONTH: 01
YEAR: 2007
Spectroscopic and Functional Characterization of Human beta-Synuclein. Information
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LANGUAGE: eng
NlmUniqueID: 9441434
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Grant and Affiliation Information for Spectroscopic and Functional Characterization of Human beta-Synuclein.
AFFILIATION: Department of Molecular Science and Technology, Graduate School of Interdisciplinary Program, Ajou University, Suwon, South Korea, 443-749. doohunkim@ajou.ac.kr.
Country: Netherlands
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MEDLINETA: Protein Pept Lett
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