Specificity of cellular interaction in Streptococcus mitis ATCC 903. Inhibition of aggregation by carbohydrates.

Specificity of cellular interaction in Streptococcus mitis ATCC 903. Inhibition of aggregation by carbohydrates. Research Abstract Details 

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Specificity of cellular interaction in Streptococcus mitis ATCC 903. Inhibition of aggregation by carbohydrates. Abstract Text:

S Abaas,T Holme,

To demonstrate the specificity of cellular interaction in the spontaneous aggregation of Streptococcus mitis ATCC 903 the inhibitory effect of various sugars was studied. More than 90% inhibition was recorded in 0.1 M concentrations of D-glucosamine, D-galactosamine and D-mannosamine. A reduction of the inhibition by more than 50% was observed when the N-acetylated derivatives of the hexosamines were tested. Polymers containing hexosamines such as hyaluronic acid, heparin and fetuin were potent inhibitors, in contrast to dextrans of different molecular weights. Inhibition was less than 20% in lactose, melibiose, cellobiose, methyl beta-D-galactopyranoside and a number of other sugars tested in 0.1 M concentration. The bacteria retained their ability to aggregate after removal of the inhibitory sugars by washing in phosphate buffer. These findings support the hypothesis that the specific nature of the spontaneous aggregation of S.mitis ATCC 903 depends on a lectin-ligand type interaction.

Specificity of cellular interaction in Streptococcus mitis ATCC 903. Inhibition of aggregation by carbohydrates. Publishing Authors By Initials

S Abaas,T Holme,

For similar proteins: fetal proteins: alpha-fetoproteins research abstracts see: proteins: fetal proteins: alpha-fetoproteins research

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Specificity of cellular interaction in Streptococcus mitis ATCC 903. Inhibition of aggregation by carbohydrates. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Acta pathologica, microbiologica, et immunologica

VOLUME: 91

Page Numbers: 419-24

Journal Abbreviation:

ISSN: 0108-0180

DAY: 12

MONTH: Dec

YEAR: 1983

Specificity of cellular interaction in Streptococcus mitis ATCC 903. Inhibition of aggregation by carbohydrates. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 8206623

Specificity of cellular interaction in Streptococcus mitis ATCC 903. Inhibition of aggregation by carbohydrates. Keywords Mesh Terms:

KEYWORDS: alpha-Fetoproteins

MESH TERMS: pharmacology

Chemical & Substance for Abstract: Specificity of cellular interaction in Streptococcus mitis ATCC 903. Inhibition of aggregation by carbohydrates. Information

Substance Name: Heparin

Registry Number: 9005-49-6

Grant and Affiliation Information for Specificity of cellular interaction in Streptococcus mitis ATCC 903. Inhibition of aggregation by carbohydrates.

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Country: DENMARK

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MEDLINETA: Acta Pathol Microbiol Immunol

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