Specific types of abnormal ciliary motility in Kartagener's syndrome and analogous respiratory disorders. A quantified microphoto-oscillographic investigation of 27 patients.

Specific types of abnormal ciliary motility in Kartagener's syndrome and analogous respiratory disorders. A quantified microphoto-oscillographic investigation of 27 patients. Research Abstract Details 

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Specific types of abnormal ciliary motility in Kartagener's syndrome and analogous respiratory disorders. A quantified microphoto-oscillographic investigation of 27 patients. Abstract Text:

M Pedersen,

Twenty seven patients with clinical evidence of lack of mucociliary activity of cilia, which include Kartagener's syndrome and termed in recent years immotile cilia syndrome or primary ciliary dyskinesia, were studied by a newly developed microphoto oscillografic technique, to determine different qualities in the ciliary motility pattern in vitro. Abnormal ciliary motility was compared to the findings at transmission electron microscopy. The patients could be allocated to groups, characterized by different abnormalities in ultrastructure and function. One patient who lacked both inner and outer dynein arms, and had total ciliary immotility. Eight who only lacked outer dynein arms had a low beating frequency, reduced number of cells with motile cilia and ciliary asynchrony. Seven with microtubular disarrangement (spoke defect) had cilia which beat asynchroneously and with short, stiff strokes. Two patients had random orientation of ciliary axes and one supernumerous microtubules, all were characterized by slight ciliary asynchrony. Eight patients had normal cilia ultrastructure, but an abnormal beating pattern, usual characterized by hyperfrequent and trembling ciliary movements (hypermotile). These groups seem to constitute separate types of congenital ciliary defects.

Specific types of abnormal ciliary motility in Kartagener's syndrome and analogous respiratory disorders. A quantified microphoto-oscillographic investigation of 27 patients. Publishing Authors By Initials

M Pedersen,

For similar respiratory tract diseases research abstracts see: respiratory tract diseases research

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Specific types of abnormal ciliary motility in Kartagener's syndrome and analogous respiratory disorders. A quantified microphoto-oscillographic investigation of 27 patients. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: European journal of respiratory diseases. Suppleme

VOLUME: 127

Page Numbers: 78-90

Journal Abbreviation:

ISSN: 0106-4347

DAY: 21

MONTH: 02

YEAR: 1983

Specific types of abnormal ciliary motility in Kartagener's syndrome and analogous respiratory disorders. A quantified microphoto-oscillographic investigation of 27 patients. Information

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LANGUAGE: eng

NlmUniqueID: 8010618

Specific types of abnormal ciliary motility in Kartagener's syndrome and analogous respiratory disorders. A quantified microphoto-oscillographic investigation of 27 patients. Keywords Mesh Terms:

KEYWORDS: Respiratory Tract Diseases

MESH TERMS: physiopathology

Chemical & Substance for Abstract: Specific types of abnormal ciliary motility in Kartagener's syndrome and analogous respiratory disorders. A quantified microphoto-oscillographic investigation of 27 patients. Information

Substance Name: Dynein ATPase

Registry Number: EC 3.6.4.2

Grant and Affiliation Information for Specific types of abnormal ciliary motility in Kartagener's syndrome and analogous respiratory disorders. A quantified microphoto-oscillographic investigation of 27 patients.

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Country: DENMARK

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MEDLINETA: Eur J Respir Dis Suppl

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