Some enzymatic properties of peptidyl dipeptide hydrolase (angiotensin I-converting enzyme).

Some enzymatic properties of peptidyl dipeptide hydrolase (angiotensin I-converting enzyme). Research Abstract Details 

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Some enzymatic properties of peptidyl dipeptide hydrolase (angiotensin I-converting enzyme). Abstract Text:

G Oshima,K Nagasawa,

Peptidyldipeptide hydrolase [angiotensin I-converting enzyme, EC 3.4.15.1] was inhibited by inorganic and organic phosphorus compounds tested, except for beta-glycerophosphate, 5'-AMP, and 5'-ADP, at the reagent concentrations used. Orthophosphate and pyrophosphate nonspecifically inhibited the enzyme activity. The enzyme was also inhibited specifically by carboxylates. The degree of inhibition by aliphatic monocarboxylates increased in proportion to their chain length up to C14. Aromatic and omega-phenylalkylcarboxylates also inhibited the enzyme activity. The enzyme was noncompetitively inhibited by acetate, 3-phenylpropionate and laurate. The Ki's for acetate, 3-phenylpropionate, and laurate were 60, 3.3, and 2.5 mM, respectively.

Some enzymatic properties of peptidyl dipeptide hydrolase (angiotensin I-converting enzyme). Publishing Authors By Initials

G Oshima,K Nagasawa,

For similar animals: chordata: vertebrates: mammals: artiodactyla: swine research abstracts see: animals: chordata: vertebrates: mammals: artiodactyla: swine research

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Some enzymatic properties of peptidyl dipeptide hydrolase (angiotensin I-converting enzyme). Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Journal of biochemistry

VOLUME: 81

Page Numbers: 57-63

Journal Abbreviation: J. Biochem.

ISSN: 0021-924X

DAY: 19

MONTH: Jan

YEAR: 1977

Some enzymatic properties of peptidyl dipeptide hydrolase (angiotensin I-converting enzyme). Information

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LANGUAGE: eng

NlmUniqueID: 376600

Some enzymatic properties of peptidyl dipeptide hydrolase (angiotensin I-converting enzyme). Keywords Mesh Terms:

KEYWORDS: Swine

MESH TERMS: pharmacology

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Substance Name: Phosphates

Registry Number: 0

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Country: JAPAN

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MEDLINETA: J Biochem

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