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Some cerebral proteins and enzyme systems in Alzheimer's presenile and senile dementia.

Some cerebral proteins and enzyme systems in Alzheimer's presenile and senile dementia. Research Abstract Details 

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  • Some cerebral proteins and enzyme systems in Alzheimer's presenile and senile dementia. Abstract Text:

    The water-soluble proteins of the cerebral gray matter and some enzyme systems (cholinesterase, acetylcholinesterase, lactate dehydrogenase, malate dehydrogenase, acid phosphatase) were studied in 9 autopsy cases of Alzheimer's presenile or senile dementia, 1 case of Pick's disease and 1 case of cerebral arteriosclerosis. The proteins and enzyme patterns were visualized on polyacrylamide gradient gels after electrophoresis. In all patients studied, the profiles of cerebral gray-matter proteins were normal. In the patients with advanced dementia, the enzyme patterns usually were abnormal. Particularly in Alzheimer's disease, the activity of malate dehydrogenase was markedly increased.

    Some cerebral proteins and enzyme systems in Alzheimer's presenile and senile dementia. Publishing Authors By Initials

    For similar proteins: nerve tissue proteins research abstracts see: proteins: nerve tissue proteins research

    PUBMED ID PMID:

    MEDLINE DATE:

    Some cerebral proteins and enzyme systems in Alzheimer's presenile and senile dementia. Journal Published:

    PUBLICATION TYPE: Journal Article

    Journal: Journal of the American Geriatrics Society

    VOLUME: 24

    Page Numbers: 12-6

    Journal Abbreviation: J Am Geriatr Soc

    ISSN: 0002-8614

    DAY: 10

    MONTH: Jan

    YEAR: 1976

    Some cerebral proteins and enzyme systems in Alzheimer's presenile and senile dementia. Information

    Number of References:

    LANGUAGE: eng

    NlmUniqueID: 7503062

    Some cerebral proteins and enzyme systems in Alzheimer's presenile and senile dementia. Keywords Mesh Terms:

    KEYWORDS: Nerve Tissue Proteins

    MESH TERMS: metabolism

    Chemical & Substance for Abstract: Some cerebral proteins and enzyme systems in Alzheimer's presenile and senile dementia. Information

    Substance Name: Acid Phosphatase

    Registry Number: EC 3.1.3.2

    Grant and Affiliation Information for Some cerebral proteins and enzyme systems in Alzheimer's presenile and senile dementia.

    AFFILIATION:

    Country: UNITED STATES

    UNITED STATES Research PublicationUNITED STATES Research Publication

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    ACRONYM:

    MEDLINETA: J Am Geriatr Soc

    REFSOURCE:

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