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Slow-flow vascular malformations of the pons: capillary telangiectasias?

Slow-flow vascular malformations of the pons: capillary telangiectasias? Research Abstract Details 

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  • Slow-flow vascular malformations of the pons: capillary telangiectasias? Abstract Text:

    l guibaudL Guibaud,m pelizzariM Pelizzari,a l guibalA L Guibal,j p pracrosJ P Pracros,c rousselleC Rousselle,

    PURPOSE: To report clinical and MR features that suggest telangiectatic vascular malformations of the pons: METHODS: The MR scans and clinical data of 12 patients demonstrating an enhancing pontine lesion with minimal or no signal abnormality on T2-weighted images were reviewed. None of the patients underwent angiography or biopsy. Follow-up scans, available for all patients between 3 weeks and 40 months (range, 11.5 months), were reviewed. RESULTS: The patients presented with a variety of symptoms including headache (n = 4), vertigo (n = 3), gait abnormality (n = 3), and hearing loss (n = 2). Two were referred for biopsy or treatment of presumed pontine glioma. On precontrast MR, 3 of 12 lesions were isointense on both T1- and T2-weighted images. Three of 12 lesions were slightly hypointense on T1-weighted images and 8 of 12 were slightly hyperintense on T2-weighted images. Postgadolinium images showed a discrete focus of enhancement with irregular or brushlike borders. Eight of 12 had an anomalous draining vessel from the lesion to the surface of the pons. None demonstrated mass effect or hemorrhage. Gradient-echo sequences in 7 patients all showed marked T2 shortening, despite the absence of hemorrhage on either T1- or T2-weighted images. None of the follow-up scans showed radiographic or clinical progression. CONCLUSION: The benign clinical course, lack of mass effect, and minimal or no T2 prolongation argue against neoplasm and instead indicate a vascular cause. We suspect the decreased signal on gradient-echo sequences represents elevated intravascular deoxyhemoglobin from stagnant blood flow. The findings are atypical for cavernous angioma or classic venous malformation. Although pathologic confirmation is lacking, the radiographic features are most consistent with capillary telangiectasia or a transitional capillary-venous malformation. Despite the absence of progression or hemorrhage in any of the patients to date, the long-term prognosis currently is unknown. We emphasize the importance of recognizing the nonneoplastic nature of these lesions.

    Slow-flow vascular malformations of the pons: capillary telangiectasias? Publishing Authors By Initials

    l guibaudL Guibaud,m pelizzariM Pelizzari,al guibalAL Guibal,jp pracrosJP Pracros,c rousselleC Rousselle,

    For similar cardiovascular diseases: vascular diseases: telangiectasis research abstracts see: cardiovascular diseases: vascular diseases: telangiectasis research

    PUBMED ID PMID:

    MEDLINE DATE:

    Slow-flow vascular malformations of the pons: capillary telangiectasias? Journal Published:

    PUBLICATION TYPE: Journal Article

    Journal: AJNR. American journal of neuroradiology

    VOLUME: 17

    Page Numbers: 71-8

    Journal Abbreviation:

    ISSN: 0195-6108

    DAY: 14

    MONTH: Jan

    YEAR: 1996

    Slow-flow vascular malformations of the pons: capillary telangiectasias? Information

    Number of References:

    LANGUAGE: eng

    NlmUniqueID: 8003708

    Slow-flow vascular malformations of the pons: capillary telangiectasias? Keywords Mesh Terms:

    KEYWORDS: Telangiectasis

    MESH TERMS: physiopathology

    Chemical & Substance for Abstract: Slow-flow vascular malformations of the pons: capillary telangiectasias? Information

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    Grant and Affiliation Information for Slow-flow vascular malformations of the pons: capillary telangiectasias?

    AFFILIATION: Department of Radiology, University of California San Francisco, USA.

    Country: UNITED STATES

    UNITED STATES Research PublicationUNITED STATES Research Publication

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    MEDLINETA: AJNR Am J Neuroradiol

    REFSOURCE: AJNR Am J Neuroradiol. 1996 Oct;17(9):17

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