Six year incidence and progression of diabetic retinopathy: results from the Mauritius diabetes complication study.

Six year incidence and progression of diabetic retinopathy: results from the Mauritius diabetes complication study. Research Abstract Details 

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Six year incidence and progression of diabetic retinopathy: results from the Mauritius diabetes complication study. Abstract Text:

Robyn J Tapp,Paul Z Zimmet,C Alex Harper,Daniel J McCarty,Pierrot Chitson,Andrew M Tonkin,Stefan ,Hugh R Taylor,K G M M Alberti,Jaakko Tuomilehto,Jonathan E Shaw,

AIMS: To determine the incidence, progression and risk factors for diabetic retinopathy in the multiethnic population of Mauritius. METHOD: A longitudinal, population-based study was conducted in Mauritius, during 1987, 1992 and 1998. Participants identified through the study as having diabetes (both known and newly diagnosed, by self-report and oral glucose tolerance test) and one in four participants with impaired glucose tolerance (IGT) underwent complications screening in 1992 and 1998. Retinal photographs were taken using a TRC-50VT retinal camera in three fields of the right eye (centred on the optic disc; macula (temporal to the optic disc); and nasal to disc). Photographs were graded according to a simplified version of the Wisconsin grading system. RESULTS: The 6-year incidence of diabetic retinopathy was 23.8% (sight-threatening in 0.4%). Among those with known diabetes mellitus (KDM) and free of retinopathy at baseline the incidence of non-proliferative diabetic retinopathy (NPDR) was 29.2% and proliferative diabetic retinopathy (PDR) was 1.0%. Among those with newly diagnosed diabetes mellitus (NDM) at baseline the incidence of NPDR was 19.1% (no incident cases of PDR were found). Independent risk factors for retinopathy using the baseline population characteristics were duration of diabetes and fasting plasma glucose. CONCLUSIONS: This is one of the few recent population-based studies of diabetic retinopathy undertaken in a developing nation. The incidence of retinopathy in Mauritius was high among those with NDM at baseline, with one in five developing retinopathy over 6 years. These results support the concept that screening for diabetes is important.

Six year incidence and progression of diabetic retinopathy: results from the Mauritius diabetes complication study. Publishing Authors By Initials

RJ Tapp,PZ Zimmet,CA Harper,DJ McCarty,P Chitson,AM Tonkin,S ,HR Taylor,KG Alberti,J Tuomilehto,JE Shaw,

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Six year incidence and progression of diabetic retinopathy: results from the Mauritius diabetes complication study. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Diabetes research and clinical practice

VOLUME: 73

Page Numbers: 298-303

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ISSN: 0168-8227

DAY: 3

MONTH: 04

YEAR: 2006

Six year incidence and progression of diabetic retinopathy: results from the Mauritius diabetes complication study. Information

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LANGUAGE: eng

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AFFILIATION: Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Australia. Robyn.Tapp@med.monash.edu.au

Country: Ireland

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MEDLINETA: Diabetes Res Clin Pract

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