Six new ergosterols from the marine-derived fungus Rhizopus sp.

Six new ergosterols from the marine-derived fungus Rhizopus sp. Research Abstract Details 

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Six new ergosterols from the marine-derived fungus Rhizopus sp. Abstract Text:

Fazuo Wang,Yuchun Fang,Min Zhang,Aiqun Lin,Tianjiao Zhu,Qianqun Gu,Weiming Zhu,Fazuo Wang,Yuchun Fang,Min Zhang,Aiqun Lin,Tianjiao Zhu,Qianqun Gu,Weiming Zhu,

Six new ergosterols, including 3beta-hydroxyl-(22E, 24R)-ergosta-5,8,22-trien-7,15-dione (1), 3beta-hydroxyl-(22E, 24R)-ergosta-5,8,14,22-tetraen-7-one (2), 3beta,15beta-dihydroxyl-(22E, 24R)-ergosta-5,8(14),22-trien-7-one (3), 3beta,15alpha-dihydroxyl-(22E, 24R)-ergosta-5,8(14),22-trien-7-one (4), 3beta-hydroxyl-(22E, 24R)-ergosta-5,8(14),22-trien-7,15-dione (5), and 5alpha,8alpha-epidioxy-23,24(R)-dimethylcholesta-6,9(11),22-trien-3beta-ol (6), have been isolated from the marine-derived fungus Rhizopus sp., along with four known ones (7-10). The structures of the new compounds were determined on the basis of extensive spectroscopic data. All compounds were evaluated for their cytotoxic activities on P388, A549, HL-60, and BEL-7420 cell lines by the MTT and SRB methods.

Six new ergosterols from the marine-derived fungus Rhizopus sp. Publishing Authors By Initials

F Wang,Y Fang,M Zhang,A Lin,T Zhu,Q Gu,W Zhu,F Wang,Y Fang,M Zhang,A Lin,T Zhu,Q Gu,W Zhu,

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Six new ergosterols from the marine-derived fungus Rhizopus sp. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Steroids

VOLUME: 73

Page Numbers: 19-26

Journal Abbreviation: Steroids

ISSN: 0039-128X

DAY: 23

MONTH: 08

YEAR: 2007

Six new ergosterols from the marine-derived fungus Rhizopus sp. Information

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LANGUAGE: eng

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Grant and Affiliation Information for Six new ergosterols from the marine-derived fungus Rhizopus sp.

AFFILIATION: Key Laboratory of Marine Drugs, Chinese Ministry of Education, Institute of Marine Drugs and Food, Ocean University of China, Qingdao 266003, People's Republic of China.

Country: United States

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MEDLINETA: Steroids

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